Should aortic stiffness parameters be used in MIS-C patient follow-up?

• Published in: The international journal of cardiovascular imaging 2024-07, Vol.40 (7), p.1525-1533
• Main Authors: Uygun, Hatice, Varan, Celal, Konca, Capan, Erdem, Nurettin, Kazaz, Tanyeli Guneyligil, Turgut, Mehmet
• Format: Article
• Language: English
• Subjects: Adolescent; Age Factors; Aorta; Aorta - diagnostic imaging; Aorta - physiopathology; Aortic valve; Cardiac Imaging; Cardiology; Cardiovascular system; Case-Control Studies; Child; Child, Preschool; Control valves; Coronary artery; Diagnosis; Echocardiography, Doppler; Female; Heart; Heart valves; Humans; Imaging; Long-term effects; Male; Medicine; Medicine & Public Health; Mitral valve; Multisystem inflammatory syndrome in children; Original Paper; Parameters; Population studies; Predictive Value of Tests; Prognosis; Radiology; Statistical analysis; Stiffness; Stroke Volume; Time Factors; Time measurement; Tricuspid valve; Vascular Stiffness; Ventricular Function, Left
• ISSN: 1875-8312; 1569-5794; 1875-8312; 1573-0743
• DOI: 10.1007/s10554-024-03133-8

We evaluated the short- and long-term effects of multisystem inflammatory syndrome in children (MIS-C) on their cardiovascular system. The study population consisted of 38 MIS-C patients and 55 control patients. Standard echocardiographic measurements and aortic stiffness parameters were compared between the two groups at different time points. During the standard echocardiographic examination at the time of diagnosis, mitral valve insufficiency was detected in 42% of the cases, left ventricular systolic dysfunction in 36%, aortic valve insufficiency in 3%, tricuspid valve insufficiency in 13%, and coronary artery dilatation in 31%. The ejection fraction, pulse pressure of the experimental group were significantly lower than the control group ( p