Low tube voltage and deep-learning reconstruction for reducing radiation and contrast medium doses in thin-slice abdominal CT: a prospective clinical trial

Objectives To investigate the feasibility of low-radiation dose and low iodinated contrast medium (ICM) dose protocol combining low-tube voltage and deep-learning reconstruction (DLR) algorithm in thin-slice abdominal CT. Methods This prospective study included 148 patients who underwent contrast-en...

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Bibliographic Details
Published in:European radiology 2024-11, Vol.34 (11), p.7386-7396
Main Authors: Yoshida, Kenichiro, Nagayama, Yasunori, Funama, Yoshinori, Ishiuchi, Soichiro, Motohara, Toshihiko, Masuda, Toshiro, Nakaura, Takeshi, Ishiko, Takatoshi, Hirai, Toshinori, Beppu, Toru
Format: Article
Language:English
Subjects:
Abdomen
Algorithms
Attenuation
Computed Tomography
Contrast media
Deep learning
Diagnostic Radiology
Diagnostic systems
Electric potential
Image contrast
Image enhancement
Image processing
Image quality
Image reconstruction
Imaging
Internal Medicine
Interventional Radiology
Iodine
Learning
Machine learning
Medical imaging
Medicine
Medicine & Public Health
Neuroradiology
Patient safety
Radiation
Radiation dosage
Radiology
Ultrasound
Voltage
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Summary:Objectives To investigate the feasibility of low-radiation dose and low iodinated contrast medium (ICM) dose protocol combining low-tube voltage and deep-learning reconstruction (DLR) algorithm in thin-slice abdominal CT. Methods This prospective study included 148 patients who underwent contrast-enhanced abdominal CT with either 120-kVp (600 mgL/kg, n  = 74) or 80-kVp protocol (360 mgL/kg, n  = 74). The 120-kVp images were reconstructed using hybrid iterative reconstruction (HIR) (120-kVp-HIR), while 80-kVp images were reconstructed using HIR (80-kVp-HIR) and DLR (80-kVp-DLR) with 0.5 mm thickness. Size-specific dose estimate (SSDE) and iodine dose were compared between protocols. Image noise, CT attenuation, and contrast-to-noise ratio (CNR) were quantified. Noise power spectrum (NPS) and edge rise slope (ERS) were used to evaluate noise texture and edge sharpness, respectively. The subjective image quality was rated on a 4-point scale. Results SSDE and iodine doses of 80-kVp were 40.4% (8.1 ± 0.9 vs. 13.6 ± 2.7 mGy) and 36.3% (21.2 ± 3.9 vs. 33.3 ± 4.3 gL) lower, respectively, than those of 120-kVp (both, p  
ISSN:1432-1084
0938-7994
1432-1084
DOI:10.1007/s00330-024-10793-6