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Associations of prediabetes and sleep duration, and inflammation as a mediator in the China Health and Retirement Longitudinal Study

The objective of this study was to examine the relationship between sleep duration and prediabetes, as well as to evaluate the influence of inflammation in mediating this association. A total of 4632 participants from the China Health and Retirement Longitudinal Study (CHARLS) were included in this...

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Bibliographic Details
Published in:Sleep health 2024-08, Vol.10 (4), p.470-477
Main Authors: Duan, Yanran, Fu, Hang, Gao, Jinghong, Wang, Sufan, Chen, Changying, Zhao, Yaojun, Jiang, Shuai, Wang, Chengzeng
Format: Article
Language:English
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Summary:The objective of this study was to examine the relationship between sleep duration and prediabetes, as well as to evaluate the influence of inflammation in mediating this association. A total of 4632 participants from the China Health and Retirement Longitudinal Study (CHARLS) were included in this study, comprising both baseline and 4-year follow-up data. The prospective relationship between sleep duration and the risk of prediabetes was examined using logistic regression models. We used multinomial logistic regression to evaluate the impact of prediabetes on sleep duration changes over follow-up, assessing the role of C-reactive protein in the association using mediation analysis. Participants with short sleep duration (
ISSN:2352-7218
2352-7226
2352-7226
DOI:10.1016/j.sleh.2024.01.011