Astaxanthin supplementation ameliorates simulated heat stress by regulating physio-biochemical responses in Sirohi goats

• Published in: Veterinary research communications 2024-08, Vol.48 (4), p.2789-2796
• Main Authors: Kittur, Priyanka M., Karthiga, K., Sarma, Lipika, Gururaj, Anjali V. K., Lata, Kant, Verma, V., Samad, H. A., Chouhan, V. S., Singh, Gyanendra, Maurya, V. P.
• Format: Article
• Language: English
• Subjects: Acclimatization; Animal Feed - analysis; Animals; Antioxidants; Astaxanthin; Biomedical and Life Sciences; Brief Report; Climate change; Climate science; Creatinine; Diet - veterinary; Dietary supplements; Dietary Supplements - analysis; Enzymes; Experiments; Feeds; Female; Goat Diseases - drug therapy; Goats; Goats - physiology; Heat resistance; Heat stress; Heat Stress Disorders - drug therapy; Heat Stress Disorders - veterinary; Heat-Shock Response - drug effects; Hot Temperature; Humidity; Life Sciences; Livestock; Metabolism; Metabolites; Oxidative stress; Physiology; Respiration; Temperature effects; Variance analysis; Veterinary Medicine/Veterinary Science; Xanthophylls - administration & dosage; Xanthophylls - pharmacology; Zoology
• ISSN: 0165-7380; 1573-7446; 1573-7446
• DOI: 10.1007/s11259-024-10327-x

The present study was undertaken to assess the ameliorative effect of dietary supplementation of astaxanthin in Sirohi goats under simulated heat stress conditions. Eighteen healthy female Sirohi goats were divided equally into three groups ( n  = 6): Heat-Stressed Control (HSC), Treatment 1 (T1), and Treatment 2 (T2). During the experiment, goats in the T1 group were supplemented with astaxanthin at the rate of 25 mg/animal/day, while those in the T2 group received supplementation of 50 mg/animal/day. The experiment was conducted for 42 days: 14 days of acclimatization period, next 21 days animals were exposed to 42ºC for 6 h from 09:00 h to 15:00 h and 7 days of recovery period. On a daily basis, we recorded the physiological responses of goats and collected environmental data at the experimental site. Blood samples were collected 0 and 14th days of acclimatization, on 1st, 6th, 11th, 16th and 21st day of heat exposure and on the 7th day of the recovery period. The rectal temperature and respiration rates of the treatment groups were lower than those of the HSC group during the exposure period. Heat stress in the supplemented groups was associated with reduced levels of hepatic enzymes such as AST and ALT. Serum urea, creatinine and albumin levels were significantly ( P