Selecting oocyte donors based on anti-Müllerian hormone (AMH) concentrations: A critical analysis of using cutoff values as exclusion criterion for an in vitro embryo production program in Gir cattle

• Published in: Animal reproduction science 2024-07, Vol.266, p.107491, Article 107491
• Main Authors: Feres, Luiz Fernando Rodrigues, Siqueira, Luiz Gustavo Bruno, Palhao, Miller Pereira, dos Santos, Livia Loiola, Pfeifer, Luiz Francisco Machado, Fernandes, Carlos Antônio de Carvalho, Viana, Joao Henrique Moreira
• Format: Article
• Language: English
• Subjects: Animals; Anti-Mullerian Hormone - blood; Antral follicle count; Bos taurus indicus; Cattle - blood; Cattle - physiology; Embryo Culture Techniques - veterinary; Embryo Transfer - veterinary; Endocrine markers; Female; Fertilization in Vitro - veterinary; Oocyte Donation - veterinary; Oocyte Retrieval - methods; Oocyte Retrieval - veterinary; Oocytes; Oocytes - physiology
• ISSN: 0378-4320; 1873-2232; 1873-2232
• DOI: 10.1016/j.anireprosci.2024.107491

The aims of this study were to determine anti-müllerian hormone (AMH) cutoff values for selecting Gir (Bos taurus indicus) oocyte donors and estimate the impact of using AMH concentrations as a selection criterion. In Exp. 1, Gir heifers (n=120) were sampled for AMH analysis and submitted to ovum pick-up and in vitro embryo production (OPU-IVEP). AMH cutoff values were calculated using ROC analysis or, alternatively, by the successive exclusion of heifers with the lowest AMH values. The correlations between AMH and OPU-IVEP outcomes were significant (P