Gastroschisis and septo‐optic‐pituitary dysplasia: Is there an association?

Aim There are several case reports describing patients with both optic nerve hypoplasia/septo‐optic‐pituitary dysplasia (ONH/SOD) and gastroschisis (GS). Our aim was to investigate whether ONH/SOD is associated with GS. Methods A retrospective population‐based study was undertaken using the Populati...

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Bibliographic Details
Published in:Journal of paediatrics and child health 2024-07, Vol.60 (7), p.294-298
Main Authors: Salman, Michael S, Ruth, Chelsea A, Yogendran, Marina S, Zrinyi, Anna, Morris, Melanie
Format: Article
Language:English
Subjects:
case control study
congenital anomaly
gastroschisis
optic nerve hypoplasia
paediatrics
Pediatrics
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Summary:Aim There are several case reports describing patients with both optic nerve hypoplasia/septo‐optic‐pituitary dysplasia (ONH/SOD) and gastroschisis (GS). Our aim was to investigate whether ONH/SOD is associated with GS. Methods A retrospective population‐based study was undertaken using the Population Research Data Repository at the Manitoba Center for Health Policy in Manitoba, Canada to investigate if any patient with ONH/SOD also had GS. In addition, Winnipeg's Surgical Database of Outcomes and Management (WiSDOM), a hospital‐based paediatric surgical database, was searched to ascertain if any of the patients with GS also have ONH/SOD. Results Cases were 124 patients with ONH/SOD diagnosed during 1990–2019. None had GS. The surgical database had 188 patients from Manitoba with GS during 1991–2019. None had ONH/SOD. Conclusion There does not appear to be an association between ONH/SOD and GS in our cohorts of patients with these two disorders.
ISSN:1034-4810
1440-1754
1440-1754
DOI:10.1111/jpc.16568