Development and Internal Validation of Nomograms for Survival of Advanced Epithelial Ovarian Cancer Based on Established Prognostic Factors and Hematologic Parameters

To assess the association between pretreatment thrombocytosis, anemia, and leukocytosis and overall survival (OS) of advanced-stage EOC. Furthermore, to develop nomograms using established prognostic factors and pretreatment hematologic parameters to predict the OS of advanced EOC patients. : Advanc...

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Bibliographic Details
Published in:Journal of clinical medicine 2024-05, Vol.13 (10), p.2789
Main Authors: Said, Sherin Abdo, IntHout, Joanna, den Ouden, Judith E, Walraven, Janneke E W, van der Aa, Maaike A, de Hullu, Joanne A, van Altena, Anne M
Format: Article
Language:English
Subjects:
Anemia
Calibration
Cancer therapies
Care and treatment
Chemotherapy
Evaluation
Hemoglobin
Leukocytes
Medical prognosis
Mortality
Netherlands
Nomograms
Ovarian cancer
Prognosis
Surgery
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Summary:To assess the association between pretreatment thrombocytosis, anemia, and leukocytosis and overall survival (OS) of advanced-stage EOC. Furthermore, to develop nomograms using established prognostic factors and pretreatment hematologic parameters to predict the OS of advanced EOC patients. : Advanced-stage EOC patients treated between January 1996 and January 2010 in eastern Netherlands were included. Survival outcomes were compared between patients with and without pretreatment thrombocytosis (≥450,000 platelets/µL), anemia (hemoglobin level of
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm13102789