The Risk of Venous Thromboembolism and Ischemic Stroke Stratified by VTE Risk Following Multiple Myeloma: A Korean Population-Based Cohort Study

: Multiple myeloma (MM) is associated with high morbidity and mortality, with elevated rates of arterial thrombosis and venous thromboembolism (VTE) and ischemic stroke (IS). We aimed to estimate the incidence of VTE and IS categorized by the VTE risk grade among individuals with MM in Korea. Additi...

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Bibliographic Details
Published in:Journal of clinical medicine 2024-05, Vol.13 (10), p.2829
Main Authors: Han, Hyun Jin, Kim, Miryoung, Lee, Jiyeon, Suh, Hae Sun
Format: Article
Language:English
Subjects:
Body mass index
Care and treatment
Chemotherapy
Codes
Cohort analysis
Comorbidity
Diagnosis
Drug dosages
Immunomodulators
Ischemia
Mortality
Multiple myeloma
Risk assessment
Risk factors
Stroke
Stroke (Disease)
Thromboembolism
Thrombosis
Variables
Venous thrombosis
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Summary:: Multiple myeloma (MM) is associated with high morbidity and mortality, with elevated rates of arterial thrombosis and venous thromboembolism (VTE) and ischemic stroke (IS). We aimed to estimate the incidence of VTE and IS categorized by the VTE risk grade among individuals with MM in Korea. Additionally, we explored the potential of the IMPEDE VTE score as a tool for assessing IS risk in patients with MM. : This retrospective cohort study comprised 37,168 individuals aged ≥ 18 years newly diagnosed with MM between January 2008 and December 2021 using the representative claims database of the Korean population. The risk of the incidence of VTE and IS within 6 months after MM diagnosis was stratified based on high-risk (IMPEDE VTE score ≥ 8) and low-risk (
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm13102829