Glyphosate contamination of drinking water and the occurrence of oxidative stress: Exposure assessment to rural Brazilian populations

• Published in: Environmental toxicology and pharmacology 2024-06, Vol.108, p.104476-104476, Article 104476
• Main Authors: Nunes, Rafaella Ferreira Nascimento, Marciano, Luiz Paulo Aguiar, Oliveira, Geovana Sousa, Cardoso, Naiane Silva, Paula, Fernanda Borges de Araújo, Sarpa, Marcia, Martins, Isarita
• Format: Article
• Language: English
• Subjects: Drinking water; Exposure assessment; Farmers; Glyphosate and AMPA
• ISSN: 1382-6689; 1872-7077
• DOI: 10.1016/j.etap.2024.104476

Studies reported that continuous application of glyphosate can cause disturbance in aquatic/terrestrial environments. As such, the objective of this study is to discuss the risk of exposure to the herbicide in drinking water and to assess the oxidative stress in the consumers rural populations of Casimiro de Abreu/ RJ and Paraguaçu/ MG, Brazil. For this, water samples (n=69) were analysed from the home of volunteers, by FMOC derivatizing- LC-FLD method. The oxidative stress was analysed determining lipid peroxidation (MAD) and defense enzymes (SOD and CAT) in serum samples from rural population (n=42) compared to urban residents (n= 42). Results of the analysis from drinking water, despite the low and moderate risk, by the hazard quotient (HQ), revealed that the population is environmentally exposed to the glyphosate. The relevant findings showed that is important to implement monitoring/ biomonitoring programs to prevent pollution and toxic effects in the rural populations. •Water analysis showed glyphosate environmental exposure to farmers•MAD increase and SOD and CAT decrease were found rural population•Biomarker analysis indicated oxidative imbalance from farmers•Hazard Quotient (HQ) characterized the risk as low to moderate from drinking water source•Results revealed the importance of pesticides monitoring programs and surveillance health