Comparison of intraocular pressure and anterior segment parameters in subjects with asymmetrical primary angle closure disease

• Published in: Clinical & experimental ophthalmology 2024-09, Vol.52 (7), p.724-731
• Main Authors: Tan, Shayne S., Tun, Tin A., Aung, Tin, Nongpiur, Monisha E.
• Format: Article
• Language: English
• Subjects: Aged; Anterior chamber; Anterior Eye Segment - diagnostic imaging; anterior segment; anterior segment imaging; asymmetrical primary angle closure; biometric; Eye; Female; Glaucoma; Glaucoma, Angle-Closure - diagnosis; Glaucoma, Angle-Closure - physiopathology; Glaucoma, Angle-Closure - surgery; Gonioscopy; Humans; intraocular pressure; Intraocular Pressure - physiology; Iridectomy - methods; Iris - diagnostic imaging; Iris - pathology; Male; Middle Aged; Optic neuropathy; Peripheral neuropathy; Tomography, Optical Coherence - methods; Tonometry, Ocular
• ISSN: 1442-6404; 1442-9071; 1442-9071
• DOI: 10.1111/ceo.14402

Background To compare intraocular pressure (IOP) and anterior segment parameters between eyes with unilateral primary angle closure glaucoma (PACG) and their fellow eyes with primary angle closure (PAC) or primary angle closure suspect (PACS). Methods Subjects underwent anterior segment imaging using 360‐degree swept‐source optical coherence tomography (SS‐OCT, CASIA Tomey, Nagoya, Japan) and ocular investigations including gonioscopy and IOP measurement. Each SS‐OCT scan (divided into 8 frames, 22.5 degrees apart) was analysed and an average was obtained for the following anterior segment parameters: iridotrabecular contact (ITC), angle opening distance (AOD750), iris thickness and curvature, anterior chamber width, depth and area (ACW, ACD and ACA) and lens vault (LV). Results Among 132 unilateral PACG subjects (mean age: 62.91 ± 7.2 years; 59.1% male), eyes with PACG had significantly higher presenting IOP (24.81 ± 0.94 vs. 18.43 ± 0.57 mmHg, p