No Change in Complications Following Thyroidectomy Despite Increase in Thyroid Cancer Surgeries: A Meta-Regression Analysis

The increase in thyroid cancer incidence has inevitably led to an increase in thyroid cancer surgeries. This meta-regression analysis aimed to determine if the rate of post-thyroidectomy complications changes by year. PubMed and Embase databases were used to perform a systematic literature search of...

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Bibliographic Details
Published in:Yonsei medical journal 2024-06, Vol.65 (6), p.348-355
Main Authors: Lee, Jun Sung, Lee, Jin Seok, Yun, Hyeok Jun, Kim, Seok-Mo, Chang, Hojin, Lee, Yong Sang, Yang, Juyeon, Lee, Hye Sun, Chang, Hang-Seok
Format: Article
Language:English
Subjects:
Humans
Hypocalcemia - epidemiology
Hypocalcemia - etiology
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Regression Analysis
Thyroid Neoplasms - surgery
Thyroidectomy - adverse effects
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Summary:The increase in thyroid cancer incidence has inevitably led to an increase in thyroid cancer surgeries. This meta-regression analysis aimed to determine if the rate of post-thyroidectomy complications changes by year. PubMed and Embase databases were used to perform a systematic literature search of studies published from January 1, 2005, using the keywords "thyroidectomy" and "complication." A meta-regression was performed for post-thyroidectomy hypocalcemia and bleeding. This meta-analysis included 25 studies involving 927751 individuals. Through the years of publications in this study, there was no significant difference in the proportion of post-thyroidectomy hypocalcemia and bleeding ( =0.9978, 0.6393). Although the number of thyroid surgeries has recently increased, the incidence of post-thyroidectomy hypocalcemia and bleeding did not significantly increase.
ISSN:0513-5796
1976-2437
DOI:10.3349/ymj.2023.0266