The need for optimal crossover in trials testing the anticipation of treatments: A methodological and ethical issue

Quality of control arms in randomized clinical trials implies also optimal postprotocol treatment. Meta‐research studies highlighting biases of the published literature contribute to improving design and conduct of future studies.

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Bibliographic Details
Published in:Cancer 2024-08, Vol.130 (16), p.2743-2745
Main Author: Di Maio, Massimo
Format: Article
Language:English
Subjects:
Clinical trials
Clinical Trials as Topic - ethics
Cross-Over Studies
Humans
Research Design - standards
Citations: Items that this one cites
Online Access:Get full text
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Description
Summary:Quality of control arms in randomized clinical trials implies also optimal postprotocol treatment. Meta‐research studies highlighting biases of the published literature contribute to improving design and conduct of future studies.
ISSN:0008-543X
1097-0142
1097-0142
DOI:10.1002/cncr.35370