Bilateral axial length growth patterns of myopic anisometropes undergoing sequential monocular to binocular orthokeratology treatment

• Published in: Contact lens & anterior eye 2024-10, Vol.47 (5), p.102192, Article 102192
• Main Authors: Chen, Yiye, Gu, Victoria Y., Xu, Yangyang, Ye, Bin, Kang, Xiaoli, Li, Bin
• Format: Article
• Language: English
• Subjects: Adolescent; Anisometropia; Anisometropia - physiopathology; Anisometropia - therapy; Axial length; Axial Length, Eye - physiopathology; Child; Female; Humans; Male; Myopia - physiopathology; Myopia - therapy; Myopia control; Orthokeratologic Procedures; Orthokeratology; Refraction, Ocular - physiology; Retrospective Studies; Treatment Outcome; Vision, Binocular - physiology
• ISSN: 1367-0484; 1476-5411; 1476-5411
• DOI: 10.1016/j.clae.2024.102192

To investigate bilateral axial length (AL) growth patterns and interactions of myopic eyes in anisometropic children during unilateral orthokeratology (OK) treatment in their singularly myopic eyes (Eyes1), followed by bilateral treatment when their second eyes (Eyes2) developed myopia. This study enrolled 94 eyes from 47 anisometropes (20 males). All patients had undergone monocular OK treatment for > 1 year followed by binocular treatment for > 1 year. Axial growth of Eyes1 and Eyes2 during the first year of monocular treatment (Stage 1), average annual axial elongation during the monocular treatment period, and axial elongation during the first year of binocular treatment (Stage 2) were respectively termed: S1E1 and S1E2, Annual E1 and Annual E2, and S2E1 and S2E2. Associations between AL growth and age, sex, interval time, and ocular parameters were analysed using correlation and generalised estimating equation (GEE) analysis. During the monocular period, Eyes1 showed less AL growth (S1E1: 0.05 ± 0.18 mm; Annual E1: 0.05 ± 0.21 mm) than Eyes2 (S1E2: 0.51 ± 0.24 mm; Annual E2: 0.52 ± 0.25 mm) (all p