Evaluating the incidence of complications among people with diabetes according to age of onset: Findings from the UK Biobank

Aims To examine the impact of current age, age at diagnosis, and duration of diabetes on the incidence rate of complications among people with type 2 diabetes. Methods Baseline data from 19,327 individuals with type 2 diabetes in the UK Biobank were analysed. Poisson regression was used to model inc...

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Bibliographic Details
Published in:Diabetic medicine 2024-09, Vol.41 (9), p.e15349-n/a
Main Authors: Sajjadi, Seyedeh Forough, Sacre, Julian W., Carstensen, Bendix, Ruiz‐Carmona, Sergio, Shaw, Jonathan E., Magliano, Dianna J.
Format: Article
Language:English
Subjects:
Age
Anxiety
Biobanks
Cerebral infarction
Congestive heart failure
Diabetes
diabetes complications
Diabetes mellitus (non-insulin dependent)
Diagnosis
incidence rate
Kidney diseases
Liver diseases
Mental depression
Myocardial infarction
type 2 diabetes
young‐onset type 2 diabetes
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Summary:Aims To examine the impact of current age, age at diagnosis, and duration of diabetes on the incidence rate of complications among people with type 2 diabetes. Methods Baseline data from 19,327 individuals with type 2 diabetes in the UK Biobank were analysed. Poisson regression was used to model incidence rates by current age, age at diagnosis, and duration of diabetes for the following outcomes: myocardial infarction (MI), heart failure (HF), stroke, end‐stage kidney diseases (ESKD), chronic kidney diseases (CKD), liver diseases, depression, and anxiety. Results The mean age at baseline was 60.2 years, and median follow‐up was 13.9 years. Diabetes duration was significantly longer among those with younger‐onset type 2 diabetes (diagnosed at
ISSN:0742-3071
1464-5491
1464-5491
DOI:10.1111/dme.15349