Neuroendocrine Tumours of Extrahepatic Biliary Tract: Report of Four Cases with Literature Review

Neuroendocrine tumours (NETs) originating from extrahepatic bile duct are an extremely rare entity. They are typically slow growing tumours with malignant potential. Commonly presenting as obstructive jaundice, preoperative clinico-radiologic differentiation between extrahepatic biliary tract neuroe...

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Bibliographic Details
Published in:Indian journal of surgical oncology 2024-05, Vol.15 (Suppl 2), p.212-217
Main Authors: Chopde, Amit, Gupta, Vikas, Jadhav, Akshaya, Kumar, Rajiv, Ramadwar, Mukta, Patkar, Shraddha, Goel, Mahesh
Format: Article
Language:English
Subjects:
Medicine
Medicine & Public Health
Oncology
Original Article
Surgery
Surgical Oncology
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Summary:Neuroendocrine tumours (NETs) originating from extrahepatic bile duct are an extremely rare entity. They are typically slow growing tumours with malignant potential. Commonly presenting as obstructive jaundice, preoperative clinico-radiologic differentiation between extrahepatic biliary tract neuroendocrine tumours and cholangiocarcinoma is difficult and the final diagnosis is usually established after surgical histopathology and immunohistochemistry examination. R0 resection offers the only curative option with good long-term outcomes for well-differentiated NETs (grade1, grade2, and grade3) while the aggressive poorly differentiated neuroendocrine carcinoma (NEC) needs multimodality approach. We present our experience of management of four cases including three cases of grade II NET and one case of NEC undergoing surgical resection at a single centre with a short review of available literature.
ISSN:0975-7651
0976-6952
DOI:10.1007/s13193-022-01621-8