The Reproductive Lifespan of Ovarian Follicle

The functional unit within mammalian ovaries is the ovarian follicle. The development of the ovarian follicle is a lengthy process beginning from the time of embryogenesis, passing through multiple different stages of maturation. The purpose of this review is to describe the most basic events in the...

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Bibliographic Details
Published in:Reproductive sciences (Thousand Oaks, Calif.) Calif.), 2024-09, Vol.31 (9), p.2604-2614
Main Authors: Kalinderi, Kallirhoe, Kalinderis, Michail, Papaliagkas, Vasileios, Fidani, Liana
Format: Article
Language:English
Subjects:
Embryology
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Reproductive Biology: Review
Reproductive Medicine
Citations: Items that this one cites
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Summary:The functional unit within mammalian ovaries is the ovarian follicle. The development of the ovarian follicle is a lengthy process beginning from the time of embryogenesis, passing through multiple different stages of maturation. The purpose of this review is to describe the most basic events in the journey of ovarian follicle development, discussing the importance of ovarian reserve and highlighting the role of several factors that affect oocyte quality and quantity during aging including hormonal, genetic and epigenetic factors. Novel, promising anti-aging strategies are also discussed. Graphical Abstract
ISSN:1933-7191
1933-7205
1933-7205
DOI:10.1007/s43032-024-01606-8