Comparative analysis of the performance of hepatobiliary agents in depicting MRI features of microvascular infiltration in hepatocellular carcinoma

Objective To compare the ability to depict MRI features of hepatobiliary agents in microvascular infiltration (MVI) of hepatocellular carcinoma (HCC) during different stages of dynamic enhancement MRI. Materials and methods A retrospective study included 111 HCC lesions scanned with either Gd-EOB-DT...

Full description

Saved in:
Bibliographic Details
Published in:Abdominal imaging 2024-07, Vol.49 (7), p.2242-2249
Main Authors: Yao, Wei-Wei, Zhang, Han-Wen, Ma, Yu-Pei, Lee, Jia-Min, Lee, Rui-ting, Wang, Yu-li, Liu, Xiao-lei, Shen, Xin-Ping, Huang, Biao, Lin, Fan
Format: Article
Language:English
Subjects:
Adult
Aged
Carcinoma, Hepatocellular - diagnostic imaging
Carcinoma, Hepatocellular - pathology
Chi-square test
Comparative analysis
Contrast agents
Contrast Media
Correlation
Female
Gadolinium
Gadolinium DTPA
Gastroenterology
Hepatobiliary
Hepatocellular carcinoma
Hepatology
Humans
Image Enhancement - methods
Imaging
Infiltration
Liver cancer
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - pathology
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
Medicine
Medicine & Public Health
Meglumine - analogs & derivatives
Metastases
Microvasculature
Microvessels - diagnostic imaging
Microvessels - pathology
Middle Aged
Organometallic Compounds
Pathology
Radiology
Retrospective Studies
Statistical analysis
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective To compare the ability to depict MRI features of hepatobiliary agents in microvascular infiltration (MVI) of hepatocellular carcinoma (HCC) during different stages of dynamic enhancement MRI. Materials and methods A retrospective study included 111 HCC lesions scanned with either Gd-EOB-DTPA or Gd-BOPTA. All cases underwent multiphase dynamic contrast-enhanced scanning before surgery, including arterial phase (AP), portal venous phase (PVP), transitional phase (TP), delayed phase (DP), and hepatobiliary phase (HBP). Two abdominal radiologists independently evaluated MRI features of MVI in HCC, such as peritumoral hyperenhancement, incomplete capsule, non-smooth tumor margins, and peritumoral hypointensity. Finally, the results were reviewed by the third senior abdominal radiologist. Chi-square (χ 2 ) Inspection for comparison between groups. P 
ISSN:2366-0058
2366-004X
2366-0058
DOI:10.1007/s00261-024-04311-x