Comparison of two endoscope channel cleaning approaches to remove cyclic build-up biofilm

• Published in: The Journal of hospital infection 2024-08, Vol.150, p.91-95
• Main Authors: Moshkanbaryans, L., Shah, V., Tan, L.Y., Jones, M.P., Vickery, K., Alfa, M., Burdach, J.
• Format: Article
• Language: English
• Subjects: Bacteria - isolation & purification; Biofilm; Biofilms - growth & development; Contamination; Decontamination - methods; Disinfection - methods; Endoscope; Endoscopes - microbiology; Equipment Contamination - prevention & control; Humans; Infection; Manual cleaning; Outbreak
• ISSN: 0195-6701; 1532-2939; 1532-2939
• DOI: 10.1016/j.jhin.2024.05.014

Biofilm contributes significantly to bacterial persistence in endoscope channels. Enhanced cleaning methods capable of removing biofilm from all endoscope channels are required to decrease infection risk to patients. This head-to-head study compared cyclic build-up biofilm removal of an automated endoscope channel cleaner (AECC) with standard manual cleaning according to instructions for use (IFU) in polytetrafluorethylene channels. Cyclic build-up biofilm was grown in 1.4-mm (representing air/water and auxiliary channels) and 3.7-mm (representing suction/ biopsy channels) inner diameter polytetrafluorethylene channels. All channels were tested for residual total organic carbon, protein, and viable bacteria. Internationally recognized ISO 15883-5:2021 alert levels were used as cleaning benchmarks for protein (3 μg/cm2) and total organic carbon (6 μg/cm2). The automated cleaner significantly outperformed manual cleaning for all markers assessed (protein, total organic carbon, viable bacteria) in 1.4-mm and 3.7-mm channels representing air/water/auxiliary and suction/biopsy channels, respectively. Manual cleaning failed to remove biofilm from the air/water and auxiliary channels. According to the IFU, these channels are not brushed, suggesting a potential root cause for a portion of the numerous endoscopy-associated infections reported in the literature. AECC shows potential to deliver enhanced cleaning over current practice to all endoscope channels and may thereby address infection risk.