Update on Endoscopic Treatments for Obesity

Purpose of Review Increased morbidity seen with rising obesity rates continues to place an unheralded burden on our health system. Lack of higher bariatric surgery utilization and limitations with lifestyle modification and pharmacotherapy highlights the need for additional therapies for obesity. En...

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Bibliographic Details
Published in:Current obesity reports 2024-06, Vol.13 (2), p.364-376
Main Authors: Pessorrusso, Fernanda, Mehta, Sagar V., Sullivan, Shelby
Format: Article
Language:English
Subjects:
Anti-Obesity Agents - therapeutic use
Bariatric Surgery - methods
Behavioral Therapy
Cardiology
Diabetes
Endocrinology
Endoscopy, Gastrointestinal - methods
Humans
Life Style
Medicine
Medicine & Public Health
Metabolic Diseases
Obesity - therapy
Randomized Controlled Trials as Topic
Review
Topical Collection on Obesity Treatment
Treatment Outcome
Weight Loss
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Summary:Purpose of Review Increased morbidity seen with rising obesity rates continues to place an unheralded burden on our health system. Lack of higher bariatric surgery utilization and limitations with lifestyle modification and pharmacotherapy highlights the need for additional therapies for obesity. Endoscopic bariatric and metabolic therapies (EBMT) are effective, safe treatments for obesity. Current FDA-approved EBMT are confined to gastric modalities while small bowel directed therapies are still considered investigational. This review highlights current modalities of EBMT. Recent Findings Many randomized controlled trials have been performed, including both open label and sham-controlled, which have demonstrated safety and efficacy of EBMT over lifestyle therapy alone. In addition, emerging evidence from clinical experience further supports EBMT for treatment of obesity. Summary Current evidence supports the safety and efficacy of EBMT for obesity treatment in conjunction with lifestyle therapy. They can also be used concurrently with weight loss medications to increase total weight loss.
ISSN:2162-4968
2162-4968
DOI:10.1007/s13679-024-00551-6