Twelve‐month outcomes following temperature‐controlled radiofrequency treatment of the septal swell body for nasal airway obstruction

• Published in: International forum of allergy & rhinology 2024-10, Vol.14 (10), p.1549-1557
• Main Authors: Pritikin, Jordan, Silvers, Stacey, Rosenbloom, Jeffrey, Davis, Bryan, Signore, Anthony Del, Sedaghat, Ahmad R., Tajudeen, Bobby A., Schmale, Isaac, Chandra, Rakesh
• Format: Article
• Language: English
• Subjects: Adult; Adverse events; Aged; Airway management; Body temperature; congestion; Female; Humans; Hypertrophy; Male; Middle Aged; nasal airway obstruction; Nasal Obstruction; Nasal Septum; Nose; NOSE scale; Patient Satisfaction; Prospective Studies; Quality of life; Radiofrequency Therapy; Respiratory tract; septal swell body; temperature‐controlled radiofrequency; Treatment Outcome
• ISSN: 2042-6976; 2042-6984; 2042-6984
• DOI: 10.1002/alr.23383

Background Improved nasal airway obstruction (NAO) symptoms were reported at 3 months following temperature‐controlled radiofrequency (TCRF) treatment of the septal swell body (SSB). This report provides results from assessments of the long‐term safety and efficacy of TCRF treatment of SSB hypertrophy to treat NAO through 12 months posttreatment. Methods This prospective, multicenter, long‐term, open‐label study was conducted in nine centers within the United States and included patients with severe/extreme NAO attributed to SSB hypertrophy. Outcome measures included assessments of Nasal Obstruction Symptom Evaluation Score (NOSE), Numeric Rating Scale (NRS) ease‐of‐breathing, patient satisfaction, and adverse events at 6 and 12 months. Results Of the 70 patients treated, 65 and 62 patients completed the 6‐ and 12‐month follow‐up assessments. Compared to baseline, there was a 67.5% decrease in adjusted mean NOSE scores at 6 months (mean change −49.6, 95% confidence interval [CI] −54.8 to −44.4; p