Prevalence, treatment efficacy, and risk factors of vascular complications in acute pancreatitis: A case–control study

• Published in: Journal of digestive diseases 2024-05, Vol.25 (5), p.318-327
• Main Authors: Guo, Xu, Tong, Huan, Chen, Liu Xiang, Wu, Meng Juan, Liu, Tian Qi, Mao, Xiao Xiao, Xie, Jia, Yang, Feng, Zhou, Die, Quan, Xin, Qian, Shuai Jie, Wei, Bo, Wu, Hao
• Format: Article
• Language: English
• Subjects: Acute Disease; acute pancreatitis; Adult; Aged; anticoagulant therapy; Anticoagulants - adverse effects; Anticoagulants - therapeutic use; Case-Control Studies; Computed tomography; Female; Gender; Hemoglobin; Humans; Hyperlipidemia; interventional radiology; Leukocytes; Male; Middle Aged; Multivariate analysis; Pancreatitis; Pancreatitis - complications; Pancreatitis - epidemiology; Pancreatitis - etiology; Prevalence; Retrospective Studies; risk factor; Risk Factors; Smoking; Thrombosis; Treatment Outcome; vascular complications; Vascular Diseases - epidemiology; Vascular Diseases - etiology
• ISSN: 1751-2972; 1751-2980; 1751-2980
• DOI: 10.1111/1751-2980.13275

Objective We aimed to investigate the prevalence of vascular complications in acute pancreatitis (AP), to compare patient outcomes using various treatments, and to explore the related risk factors. Methods Consecutive AP patients admitted from January 2010 to July 2017 were retrospectively included. Demographics, vascular complications, laboratory indices, and imaging findings were collected. Univariate and multivariate analyses were used to explore potential risk factors of vascular complications. Results Of 3048 AP patients, 808 (26.5%) had vascular complications, including visceral vein thrombosis, sinistral portal hypertension, and arterial complications. And 38 (4.7%) patients received anticoagulant therapy and had a higher rate of recanalization (P