Rhabdomyolysis and acute kidney injury after consumption of black seed oil

• Published in: Toxicon (Oxford) 2024-07, Vol.245, p.107787-107787, Article 107787
• Main Authors: Sener, Kemal, Cakir, Adem, Yesiloglu, Onder, Altug, Ertugrul, Guven, Ramazan, Korkut, Semih
• Format: Article
• Language: English
• Subjects: Acute Kidney Injury - chemically induced; Acute renal damage; Adult; Black seed oil; Chemical and Drug Induced Liver Injury - etiology; Hepatotoxicity; Humans; Male; Plant Oils - adverse effects; Rhabdomyolysis; Rhabdomyolysis - chemically induced; Seeds - chemistry; Side effect
• ISSN: 0041-0101; 1879-3150
• DOI: 10.1016/j.toxicon.2024.107787

Medicines derived from natural sources have been used for thousands of years throughout the world. Because natural compounds are thought to have less toxic effects and fewer side effects, these products are becoming more popular by the day. In this case report, we presented a case of acute kidney injury, rhabdomyolysis, and hepatotoxicity after ingestion of black seed oil. Although black seed oil is widely used around the world, there is currently limited knowledge on its adverse effects. It is important to keep in mind that rhabdomyolysis, acute renal damage, and hepatotoxicity might occur following the use of black seed oil. Black seed oil ingestion should be considered when making a differential diagnosis for these conditions in patients suspected of taking herbal products. •The report describes the side effect of using black cumin oil.•The patient developed rhabdomyolysis and hepatotoxicity after consumption.•The clinical picture emerged after using 2000 mg per day for 1 month.•There is not enough data in the literature about the side effects of black cumin oil.•More research is needed regarding the side effects of black seed oil.