Factors associated with sarcopenic obesity in Brazilian adults and older people: Systematic review and meta‐analysis of observational studies

• Published in: Geriatrics & gerontology international 2024-07, Vol.24 (7), p.661-674
• Main Authors: Guimarães, Nathalia Sernizon, Reis, Marcela Gomes, Tameirão, Diego Ribeiro, Castro Cezar, Natália Oiring, Leopoldino, Amanda Aparecida Oliveira, Magno, Luiz Alexandre Viana
• Format: Article
• Language: English
• Subjects: Adipose tissue; Adult; Aged; Aged, 80 and over; Aging; Body fat; Brazil; Brazil - epidemiology; Comorbidity; Epidemiology; Female; Health risks; Humans; Lifestyles; Male; Muscle strength; Obesity; Obesity - epidemiology; Observational studies; Observational Studies as Topic; Older people; Osteoarthritis; Prevalence; Public health; Quality of life; Risk Factors; Sarcopenia - epidemiology; sarcopenic obesity; Sleep apnea; Socioeconomics; Systematic review; systematic review and meta‐analysis
• ISSN: 1444-1586; 1447-0594; 1447-0594
• DOI: 10.1111/ggi.14918

Aim Sarcopenic obesity (SO) is characterized by the coexistence of the loss of muscle mass and function with excess adipose tissue. Its prevalence has increased concomitantly with population aging, becoming one of the most significant challenges for public health, threatening the quality of life and the physical and mental health of the elderly population. Methods This study estimated the prevalence and factors associated with SO among adults and the elderly in Brazil's macro‐regions, utilizing MEDLINE, Embase, Web of Science, and the Virtual Health Library databases. Primary outcomes included SO prevalence overall and by subgroups, with secondary outcomes identifying associated factors. Results A systematic review of 33 studies with 10 266 participants up to July 2023 showed a 17% prevalence of SO (95% confidence interval: 13–21%), using a random effects meta‐analysis. The Central‐West region had the highest occurrence (27%). Dual‐energy X‐ray absorptiometry (26%) and bioimpedance (6%) were the top diagnostic methods. Protective factors were chronic kidney disease and healthy lifestyles; risk factors included socioeconomic status, functionality, lifestyle, biochemical parameters, and comorbidities such as osteoarthritis and apnea. Conclusions The prevalence of SO in Brazil is significant, emerging as a critical public health problem. It is essential to direct attention to changes in prevalence rates in the coming years, given the rising obesity trends and the absolute increase in the elderly population. Geriatr Gerontol Int 2024; 24: 661–674. In Brazil, sarcopenic obesity—a condition characterized by simultaneous muscle mass loss and excess fat accumulation—affects 17% of the population, with significant regional disparities. This systematic review and meta‐analysis highlights the urgent need for public health strategies to address this growing challenge.