Long-term kidney outcomes in patients with permanent hypoparathyroidism after total thyroidectomy for benign disease: A population-based study

Permanent hypoparathyroidism is a significant complication after total thyroidectomy. This study aimed to evaluate the long-term impact of postoperative permanent hypoparathyroidism on kidney outcomes. Data of patients undergoing total thyroidectomy from 1999 to 2014 were retrieved. The estimated gl...

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Bibliographic Details
Published in:Surgery 2024-09, Vol.176 (3), p.700-707
Main Authors: Luk, Yan, Fung, Matrix Man Him, Lui, David Tak Wai, Liu, Xiaodong, Li, Lanlan, Wong, Carlos King Ho, Lang, Brian Hung Hin
Format: Article
Language:English
Subjects:
Adult
Aged
Female
Follow-Up Studies
Glomerular Filtration Rate
Humans
Hypoparathyroidism - epidemiology
Hypoparathyroidism - etiology
Kidney Failure, Chronic - surgery
Male
Middle Aged
Postoperative Complications - diagnosis
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Retrospective Studies
Risk Factors
Thyroidectomy - adverse effects
Citations: Items that this one cites
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Summary:Permanent hypoparathyroidism is a significant complication after total thyroidectomy. This study aimed to evaluate the long-term impact of postoperative permanent hypoparathyroidism on kidney outcomes. Data of patients undergoing total thyroidectomy from 1999 to 2014 were retrieved. The estimated glomerular filtration rate was determined from serum creatinine results. Permanent hypoparathyroidism was defined as requiring oral calcium and vitamin D supplements postoperatively for at least 6 months. The primary outcome was a sustained decline in the estimated glomerular filtration rate from baseline by ≥50%. Secondary outcomes were end-stage kidney disease (a composite of sustained estimated glomerular filtration rate
ISSN:0039-6060
1532-7361
1532-7361
DOI:10.1016/j.surg.2024.05.005