Risk Factors and Contemporary Management Options for Pain and Discomfort Experienced During a Prostate Biopsy

• Published in: Current urology reports 2024-10, Vol.25 (10), p.243-252
• Main Authors: Diaz, Gabriela M., Webb, Lindsey T., Rabil, Maximilian J., Lokeshwar, Soum D., Choksi, Ankur U., Leapman, Michael S., Sprenkle, Preston C.
• Format: Article
• Language: English
• Subjects: Medicine; Medicine & Public Health; Nephrology; Review; Topical Collection on Prostate Cancer; Urology
• ISSN: 1527-2737; 1534-6285; 1534-6285
• DOI: 10.1007/s11934-024-01220-w

Purpose of Review Prostate fusion biopsy, an innovative imaging modality for diagnosing prostate cancer, presents certain challenges for patients including discomfort and emotional distress, leading to nonadherence to treatment and follow-ups. To inform clinicians and offer pain relief alternatives to patients, this review delves into the risk factors for increased pain and modern management options to alleviate pain during prostate biopsy. Recent Findings Individual responses to pain vary, and the overall experience of pain during a prostate biopsy has been contributed to numerous factors such as patient age, prostate volume, previous biopsy experience, and more. As a result, several strategies aim to mitigate pain during in-office procedures. Notably, techniques including pharmacological analgesics, hand holding, heating pads, entertainment/virtual reality, and distraction have shown significant efficacy. Summary Existing studies explore risk factors influencing pain intensity during prostate biopsy and effective pain management strategies. This review consolidates available information to guide clinicians in enhancing patient comfort and thus, encourage surveillance adherence.