The association of T102C (rs6313) polymorphism in the 5-HT2A receptor gene with temporomandibular disorders and anxiety in a group of Turkish population

To investigate the relationship between T102C (rs6313) polymorphism in the 5-hydroxytryptamine receptor-2A (5HTR2A) gene and temporomandibular disorder (TMD) and anxiety. This observational case-control study included 80 patients and 70 healthy controls. TMD was diagnosed using the criteria for TMD...

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Published in:Cranio 2024-06, p.1-9
Main Authors: Ekici, Ömer, Arıkan Söylemez, Evrim Suna
Format: Article
Language:English
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Summary:To investigate the relationship between T102C (rs6313) polymorphism in the 5-hydroxytryptamine receptor-2A (5HTR2A) gene and temporomandibular disorder (TMD) and anxiety. This observational case-control study included 80 patients and 70 healthy controls. TMD was diagnosed using the criteria for TMD (DC/TMD). Anxiety was assessed with the Beck anxiety scale. A genotyping study of HTRR2A T102C (rs6313) gene polymorphism was performed from genomic DNA isolated from blood. The TMD group had higher anxiety scores than the control group (  
ISSN:0886-9634
2151-0903
2151-0903
DOI:10.1080/08869634.2024.2369729