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Incidence of Mortality and Its Relation to Comorbidity in Ludwig’s Angina: A Retrospective Study
Introduction Ludwig’s angina is a serious life-threatening infective condition of maxillofacial region due to odontogenic origin which is clinically diagnosed by its clinical signs and symptoms. Airway management and early surgical decompression is the main stay of management. The mortality rates in...
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Published in: | Journal of maxillofacial and oral surgery 2024-06, Vol.23 (3), p.581-588 |
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container_title | Journal of maxillofacial and oral surgery |
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creator | Sahoo, N. K. Thakral, Ankur Pandey, Swati Vaswani, Himani Vashisht, Sahil Maheshwari, Isha |
description | Introduction
Ludwig’s angina is a serious life-threatening infective condition of maxillofacial region due to odontogenic origin which is clinically diagnosed by its clinical signs and symptoms. Airway management and early surgical decompression is the main stay of management. The mortality rates in Ludwig’s angina remains multivariate. There is a paucity in literature regarding the mortality rates of this disease.
Aim and Objectives
Aim of this retrospective study is to describes the characteristics, probable cause of death and mortality rates of patients with co-morbidities presenting to the emergency department (ED) who were subsequently admitted with a primary diagnosis of Ludwig’s angina.
Materials and Method
Study was conducted in the department of maxillofacial surgery in a tertiary care teaching hospital from Jan 2011 to Dec 2022. Data of 17 patients who were clinically diagnosed as Ludwig’s angina were included in the study. The comorbidity, source of odontongenic cause, mode of intubation and the outcome of the disease were evaluated.
Result
Comparison of categorical variables was done using Fishers exact test. A p-value of |
doi_str_mv | 10.1007/s12663-024-02116-5 |
format | article |
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Ludwig’s angina is a serious life-threatening infective condition of maxillofacial region due to odontogenic origin which is clinically diagnosed by its clinical signs and symptoms. Airway management and early surgical decompression is the main stay of management. The mortality rates in Ludwig’s angina remains multivariate. There is a paucity in literature regarding the mortality rates of this disease.
Aim and Objectives
Aim of this retrospective study is to describes the characteristics, probable cause of death and mortality rates of patients with co-morbidities presenting to the emergency department (ED) who were subsequently admitted with a primary diagnosis of Ludwig’s angina.
Materials and Method
Study was conducted in the department of maxillofacial surgery in a tertiary care teaching hospital from Jan 2011 to Dec 2022. Data of 17 patients who were clinically diagnosed as Ludwig’s angina were included in the study. The comorbidity, source of odontongenic cause, mode of intubation and the outcome of the disease were evaluated.
Result
Comparison of categorical variables was done using Fishers exact test. A p-value of <0.7 was considered statistically significant. The results suggested that Out of 17 patients 12 patients (70.5%), 7 male and 5 females had comorbidities and four cases (23.5%) had complication of death, all having co-morbidities.
Summary
It concludes that associated comorbidity has a significant role in progress and outcome of the disease and incidence of death is more common in cases having associated comorbidity.</description><identifier>ISSN: 0972-8279</identifier><identifier>EISSN: 0974-942X</identifier><identifier>DOI: 10.1007/s12663-024-02116-5</identifier><identifier>PMID: 38911416</identifier><language>eng</language><publisher>New Delhi: Springer India</publisher><subject>Abscesses ; Age ; Airway management ; Angina pectoris ; Antibiotics ; Burns ; Cardiovascular disease ; Cellulitis ; Chronic obstructive pulmonary disease ; Clinical Focus ; Comorbidity ; Dentistry ; Diabetes ; Emergency medical care ; Fatalities ; Hypertension ; Infections ; Intensive care ; Intubation ; Kidney diseases ; Liver cirrhosis ; Medicine ; Medicine & Public Health ; Mortality ; Oral and Maxillofacial Surgery ; Ostomy ; Otorhinolaryngology ; Patients ; Plastic Surgery ; Tracheotomy</subject><ispartof>Journal of maxillofacial and oral surgery, 2024-06, Vol.23 (3), p.581-588</ispartof><rights>The Association of Oral and Maxillofacial Surgeons of India 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c326t-44a3034bf73b082a057309b47efd58933ca6a693cab2cc466c5c1e1f62a6715e3</cites><orcidid>0009-0009-1983-8106</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38911416$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sahoo, N. K.</creatorcontrib><creatorcontrib>Thakral, Ankur</creatorcontrib><creatorcontrib>Pandey, Swati</creatorcontrib><creatorcontrib>Vaswani, Himani</creatorcontrib><creatorcontrib>Vashisht, Sahil</creatorcontrib><creatorcontrib>Maheshwari, Isha</creatorcontrib><title>Incidence of Mortality and Its Relation to Comorbidity in Ludwig’s Angina: A Retrospective Study</title><title>Journal of maxillofacial and oral surgery</title><addtitle>J. Maxillofac. Oral Surg</addtitle><addtitle>J Maxillofac Oral Surg</addtitle><description>Introduction
Ludwig’s angina is a serious life-threatening infective condition of maxillofacial region due to odontogenic origin which is clinically diagnosed by its clinical signs and symptoms. Airway management and early surgical decompression is the main stay of management. The mortality rates in Ludwig’s angina remains multivariate. There is a paucity in literature regarding the mortality rates of this disease.
Aim and Objectives
Aim of this retrospective study is to describes the characteristics, probable cause of death and mortality rates of patients with co-morbidities presenting to the emergency department (ED) who were subsequently admitted with a primary diagnosis of Ludwig’s angina.
Materials and Method
Study was conducted in the department of maxillofacial surgery in a tertiary care teaching hospital from Jan 2011 to Dec 2022. Data of 17 patients who were clinically diagnosed as Ludwig’s angina were included in the study. The comorbidity, source of odontongenic cause, mode of intubation and the outcome of the disease were evaluated.
Result
Comparison of categorical variables was done using Fishers exact test. A p-value of <0.7 was considered statistically significant. The results suggested that Out of 17 patients 12 patients (70.5%), 7 male and 5 females had comorbidities and four cases (23.5%) had complication of death, all having co-morbidities.
Summary
It concludes that associated comorbidity has a significant role in progress and outcome of the disease and incidence of death is more common in cases having associated comorbidity.</description><subject>Abscesses</subject><subject>Age</subject><subject>Airway management</subject><subject>Angina pectoris</subject><subject>Antibiotics</subject><subject>Burns</subject><subject>Cardiovascular disease</subject><subject>Cellulitis</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Clinical Focus</subject><subject>Comorbidity</subject><subject>Dentistry</subject><subject>Diabetes</subject><subject>Emergency medical care</subject><subject>Fatalities</subject><subject>Hypertension</subject><subject>Infections</subject><subject>Intensive care</subject><subject>Intubation</subject><subject>Kidney diseases</subject><subject>Liver cirrhosis</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mortality</subject><subject>Oral and Maxillofacial Surgery</subject><subject>Ostomy</subject><subject>Otorhinolaryngology</subject><subject>Patients</subject><subject>Plastic Surgery</subject><subject>Tracheotomy</subject><issn>0972-8279</issn><issn>0974-942X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kcFqGzEQhkVISIKTF8ihCHrJZRtJo9Xu5mZM0xocCkkLuQmtVmsU1pIraVN8y2v09fokle00hRwiGEYw3_ya0Y_QBSWfKCHVVaRMCCgI4zkoFUV5gE5JU_Gi4ezhcHdnRc2q5gSdx_hI8gEKDdBjdAJ1Qymn4hS1c6dtZ5w22Pf41oekBps2WLkOz1PEd2ZQyXqHk8czv_Khtd22bh1ejN0vu_zz_DviqVtap67xNPMp-Lg2Otkng-_T2G3O0FGvhmjOX_IE_bj5_H32tVh8-zKfTReFBiZSwbkCArztK2hJzRQpKyBNyyvTd2XdAGgllGhyapnWXAhdampoL5gSFS0NTNDlXncd_M_RxCRXNmozDMoZP0YJJGMUIMcEfXyDPvoxuDzdliKUM1aLTLE9pfNKMZheroNdqbCRlMitCXJvgswmyJ0JssxNH16kx3ZluteWf1-eAdgDMZfc0oT_b78j-xcf1pFq</recordid><startdate>20240601</startdate><enddate>20240601</enddate><creator>Sahoo, N. K.</creator><creator>Thakral, Ankur</creator><creator>Pandey, Swati</creator><creator>Vaswani, Himani</creator><creator>Vashisht, Sahil</creator><creator>Maheshwari, Isha</creator><general>Springer India</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0009-0009-1983-8106</orcidid></search><sort><creationdate>20240601</creationdate><title>Incidence of Mortality and Its Relation to Comorbidity in Ludwig’s Angina: A Retrospective Study</title><author>Sahoo, N. K. ; Thakral, Ankur ; Pandey, Swati ; Vaswani, Himani ; Vashisht, Sahil ; Maheshwari, Isha</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-44a3034bf73b082a057309b47efd58933ca6a693cab2cc466c5c1e1f62a6715e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Abscesses</topic><topic>Age</topic><topic>Airway management</topic><topic>Angina pectoris</topic><topic>Antibiotics</topic><topic>Burns</topic><topic>Cardiovascular disease</topic><topic>Cellulitis</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Clinical Focus</topic><topic>Comorbidity</topic><topic>Dentistry</topic><topic>Diabetes</topic><topic>Emergency medical care</topic><topic>Fatalities</topic><topic>Hypertension</topic><topic>Infections</topic><topic>Intensive care</topic><topic>Intubation</topic><topic>Kidney diseases</topic><topic>Liver cirrhosis</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mortality</topic><topic>Oral and Maxillofacial Surgery</topic><topic>Ostomy</topic><topic>Otorhinolaryngology</topic><topic>Patients</topic><topic>Plastic Surgery</topic><topic>Tracheotomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sahoo, N. K.</creatorcontrib><creatorcontrib>Thakral, Ankur</creatorcontrib><creatorcontrib>Pandey, Swati</creatorcontrib><creatorcontrib>Vaswani, Himani</creatorcontrib><creatorcontrib>Vashisht, Sahil</creatorcontrib><creatorcontrib>Maheshwari, Isha</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of maxillofacial and oral surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sahoo, N. K.</au><au>Thakral, Ankur</au><au>Pandey, Swati</au><au>Vaswani, Himani</au><au>Vashisht, Sahil</au><au>Maheshwari, Isha</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Incidence of Mortality and Its Relation to Comorbidity in Ludwig’s Angina: A Retrospective Study</atitle><jtitle>Journal of maxillofacial and oral surgery</jtitle><stitle>J. Maxillofac. Oral Surg</stitle><addtitle>J Maxillofac Oral Surg</addtitle><date>2024-06-01</date><risdate>2024</risdate><volume>23</volume><issue>3</issue><spage>581</spage><epage>588</epage><pages>581-588</pages><issn>0972-8279</issn><eissn>0974-942X</eissn><abstract>Introduction
Ludwig’s angina is a serious life-threatening infective condition of maxillofacial region due to odontogenic origin which is clinically diagnosed by its clinical signs and symptoms. Airway management and early surgical decompression is the main stay of management. The mortality rates in Ludwig’s angina remains multivariate. There is a paucity in literature regarding the mortality rates of this disease.
Aim and Objectives
Aim of this retrospective study is to describes the characteristics, probable cause of death and mortality rates of patients with co-morbidities presenting to the emergency department (ED) who were subsequently admitted with a primary diagnosis of Ludwig’s angina.
Materials and Method
Study was conducted in the department of maxillofacial surgery in a tertiary care teaching hospital from Jan 2011 to Dec 2022. Data of 17 patients who were clinically diagnosed as Ludwig’s angina were included in the study. The comorbidity, source of odontongenic cause, mode of intubation and the outcome of the disease were evaluated.
Result
Comparison of categorical variables was done using Fishers exact test. A p-value of <0.7 was considered statistically significant. The results suggested that Out of 17 patients 12 patients (70.5%), 7 male and 5 females had comorbidities and four cases (23.5%) had complication of death, all having co-morbidities.
Summary
It concludes that associated comorbidity has a significant role in progress and outcome of the disease and incidence of death is more common in cases having associated comorbidity.</abstract><cop>New Delhi</cop><pub>Springer India</pub><pmid>38911416</pmid><doi>10.1007/s12663-024-02116-5</doi><tpages>8</tpages><orcidid>https://orcid.org/0009-0009-1983-8106</orcidid></addata></record> |
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subjects | Abscesses Age Airway management Angina pectoris Antibiotics Burns Cardiovascular disease Cellulitis Chronic obstructive pulmonary disease Clinical Focus Comorbidity Dentistry Diabetes Emergency medical care Fatalities Hypertension Infections Intensive care Intubation Kidney diseases Liver cirrhosis Medicine Medicine & Public Health Mortality Oral and Maxillofacial Surgery Ostomy Otorhinolaryngology Patients Plastic Surgery Tracheotomy |
title | Incidence of Mortality and Its Relation to Comorbidity in Ludwig’s Angina: A Retrospective Study |
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