Keyhole Aqueduct Syndrome

Keyhole aqueduct syndrome is a rare progressive neurodegenerative disorder describing a unique set of neuro-ophthalmologic, neuroimaging, and histopathological findings on autopsy. A midline mesencephalic cleft communicating with the cerebral aqueduct resembling syrinx is seen on imaging and histopa...

Full description

Saved in:
Bibliographic Details
Published in:Neuroradiology 2024-09, Vol.66 (9), p.1577-1580
Main Authors: Zak, Imad, Hadidchi, Shahram, Ross, Philip
Format: Article
Language:English
Subjects:
Ataxia
Atrophy
Autopsies
Autopsy
Case Report
Cavitation
Communication
Consent
Diplopia
Etiology
Females
Histopathology
Imaging
Keyholes
Medical imaging
Medicine
Medicine & Public Health
Neurodegenerative diseases
Neuroimaging
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Ophthalmoplegia
Patients
Radiology
Stroke
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c256t-23a0e9e76b9e93f752895be29fea01c21e67ce6c76f28b93ef7182d7956f94763
container_end_page 1580
container_issue 9
container_start_page 1577
container_title Neuroradiology
container_volume 66
creator Zak, Imad
Hadidchi, Shahram
Ross, Philip
description Keyhole aqueduct syndrome is a rare progressive neurodegenerative disorder describing a unique set of neuro-ophthalmologic, neuroimaging, and histopathological findings on autopsy. A midline mesencephalic cleft communicating with the cerebral aqueduct resembling syrinx is seen on imaging and histopathology. There are 9 cases published in the literature. We encountered a patient with vertical nystagmus, internuclear ophthalmoplegia, and progressive ataxia who has a midline cleft connecting the cerebral aqueduct with the interpeduncular cistern highlighting a distinguishing feature of this syndrome.
doi_str_mv 10.1007/s00234-024-03408-w
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3071514267</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3092483591</sourcerecordid><originalsourceid>FETCH-LOGICAL-c256t-23a0e9e76b9e93f752895be29fea01c21e67ce6c76f28b93ef7182d7956f94763</originalsourceid><addsrcrecordid>eNp9kE1LAzEQhoMotlZ_gB6k4MXL6uRjk82xlPqBBQ_qOexmJ9qyHzXpUvrvjW5V8OBhmMM8887wEHJG4YoCqOsAwLhIgMXiArJks0eGVHCWUM1gnwzjPEu4FjAgRyEsAYArrg7JgGeaAlViSE4fcPvWVjievHdYdnY9fto2pW9rPCYHLq8Cnuz6iLzczJ6nd8n88fZ-OpknlqVynTCeA2pUstCouVMpy3RaINMOc6CWUZTKorRKOpYVmqNTNGOl0ql0WijJR-Syz135Nv4Q1qZeBItVlTfYdsFwUDSlgkkV0Ys_6LLtfBO_i5RmIuOpppFiPWV9G4JHZ1Z-Ued-ayiYT3GmF2eiOPMlzmzi0vkuuitqLH9Wvk1FgPdAiKPmFf3v7X9iPwDKkHYB</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3092483591</pqid></control><display><type>article</type><title>Keyhole Aqueduct Syndrome</title><source>Springer Nature</source><creator>Zak, Imad ; Hadidchi, Shahram ; Ross, Philip</creator><creatorcontrib>Zak, Imad ; Hadidchi, Shahram ; Ross, Philip</creatorcontrib><description>Keyhole aqueduct syndrome is a rare progressive neurodegenerative disorder describing a unique set of neuro-ophthalmologic, neuroimaging, and histopathological findings on autopsy. A midline mesencephalic cleft communicating with the cerebral aqueduct resembling syrinx is seen on imaging and histopathology. There are 9 cases published in the literature. We encountered a patient with vertical nystagmus, internuclear ophthalmoplegia, and progressive ataxia who has a midline cleft connecting the cerebral aqueduct with the interpeduncular cistern highlighting a distinguishing feature of this syndrome.</description><identifier>ISSN: 0028-3940</identifier><identifier>ISSN: 1432-1920</identifier><identifier>EISSN: 1432-1920</identifier><identifier>DOI: 10.1007/s00234-024-03408-w</identifier><identifier>PMID: 38910174</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Ataxia ; Atrophy ; Autopsies ; Autopsy ; Case Report ; Cavitation ; Communication ; Consent ; Diplopia ; Etiology ; Females ; Histopathology ; Imaging ; Keyholes ; Medical imaging ; Medicine ; Medicine &amp; Public Health ; Neurodegenerative diseases ; Neuroimaging ; Neurology ; Neuroradiology ; Neurosciences ; Neurosurgery ; Ophthalmoplegia ; Patients ; Radiology ; Stroke</subject><ispartof>Neuroradiology, 2024-09, Vol.66 (9), p.1577-1580</ispartof><rights>This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024</rights><rights>2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.</rights><rights>This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c256t-23a0e9e76b9e93f752895be29fea01c21e67ce6c76f28b93ef7182d7956f94763</cites><orcidid>0009-0003-9845-0260</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38910174$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zak, Imad</creatorcontrib><creatorcontrib>Hadidchi, Shahram</creatorcontrib><creatorcontrib>Ross, Philip</creatorcontrib><title>Keyhole Aqueduct Syndrome</title><title>Neuroradiology</title><addtitle>Neuroradiology</addtitle><addtitle>Neuroradiology</addtitle><description>Keyhole aqueduct syndrome is a rare progressive neurodegenerative disorder describing a unique set of neuro-ophthalmologic, neuroimaging, and histopathological findings on autopsy. A midline mesencephalic cleft communicating with the cerebral aqueduct resembling syrinx is seen on imaging and histopathology. There are 9 cases published in the literature. We encountered a patient with vertical nystagmus, internuclear ophthalmoplegia, and progressive ataxia who has a midline cleft connecting the cerebral aqueduct with the interpeduncular cistern highlighting a distinguishing feature of this syndrome.</description><subject>Ataxia</subject><subject>Atrophy</subject><subject>Autopsies</subject><subject>Autopsy</subject><subject>Case Report</subject><subject>Cavitation</subject><subject>Communication</subject><subject>Consent</subject><subject>Diplopia</subject><subject>Etiology</subject><subject>Females</subject><subject>Histopathology</subject><subject>Imaging</subject><subject>Keyholes</subject><subject>Medical imaging</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Neurodegenerative diseases</subject><subject>Neuroimaging</subject><subject>Neurology</subject><subject>Neuroradiology</subject><subject>Neurosciences</subject><subject>Neurosurgery</subject><subject>Ophthalmoplegia</subject><subject>Patients</subject><subject>Radiology</subject><subject>Stroke</subject><issn>0028-3940</issn><issn>1432-1920</issn><issn>1432-1920</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LAzEQhoMotlZ_gB6k4MXL6uRjk82xlPqBBQ_qOexmJ9qyHzXpUvrvjW5V8OBhmMM8887wEHJG4YoCqOsAwLhIgMXiArJks0eGVHCWUM1gnwzjPEu4FjAgRyEsAYArrg7JgGeaAlViSE4fcPvWVjievHdYdnY9fto2pW9rPCYHLq8Cnuz6iLzczJ6nd8n88fZ-OpknlqVynTCeA2pUstCouVMpy3RaINMOc6CWUZTKorRKOpYVmqNTNGOl0ql0WijJR-Syz135Nv4Q1qZeBItVlTfYdsFwUDSlgkkV0Ys_6LLtfBO_i5RmIuOpppFiPWV9G4JHZ1Z-Ued-ayiYT3GmF2eiOPMlzmzi0vkuuitqLH9Wvk1FgPdAiKPmFf3v7X9iPwDKkHYB</recordid><startdate>20240901</startdate><enddate>20240901</enddate><creator>Zak, Imad</creator><creator>Hadidchi, Shahram</creator><creator>Ross, Philip</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7TK</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0009-0003-9845-0260</orcidid></search><sort><creationdate>20240901</creationdate><title>Keyhole Aqueduct Syndrome</title><author>Zak, Imad ; Hadidchi, Shahram ; Ross, Philip</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c256t-23a0e9e76b9e93f752895be29fea01c21e67ce6c76f28b93ef7182d7956f94763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Ataxia</topic><topic>Atrophy</topic><topic>Autopsies</topic><topic>Autopsy</topic><topic>Case Report</topic><topic>Cavitation</topic><topic>Communication</topic><topic>Consent</topic><topic>Diplopia</topic><topic>Etiology</topic><topic>Females</topic><topic>Histopathology</topic><topic>Imaging</topic><topic>Keyholes</topic><topic>Medical imaging</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Neurodegenerative diseases</topic><topic>Neuroimaging</topic><topic>Neurology</topic><topic>Neuroradiology</topic><topic>Neurosciences</topic><topic>Neurosurgery</topic><topic>Ophthalmoplegia</topic><topic>Patients</topic><topic>Radiology</topic><topic>Stroke</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zak, Imad</creatorcontrib><creatorcontrib>Hadidchi, Shahram</creatorcontrib><creatorcontrib>Ross, Philip</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroradiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zak, Imad</au><au>Hadidchi, Shahram</au><au>Ross, Philip</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Keyhole Aqueduct Syndrome</atitle><jtitle>Neuroradiology</jtitle><stitle>Neuroradiology</stitle><addtitle>Neuroradiology</addtitle><date>2024-09-01</date><risdate>2024</risdate><volume>66</volume><issue>9</issue><spage>1577</spage><epage>1580</epage><pages>1577-1580</pages><issn>0028-3940</issn><issn>1432-1920</issn><eissn>1432-1920</eissn><abstract>Keyhole aqueduct syndrome is a rare progressive neurodegenerative disorder describing a unique set of neuro-ophthalmologic, neuroimaging, and histopathological findings on autopsy. A midline mesencephalic cleft communicating with the cerebral aqueduct resembling syrinx is seen on imaging and histopathology. There are 9 cases published in the literature. We encountered a patient with vertical nystagmus, internuclear ophthalmoplegia, and progressive ataxia who has a midline cleft connecting the cerebral aqueduct with the interpeduncular cistern highlighting a distinguishing feature of this syndrome.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>38910174</pmid><doi>10.1007/s00234-024-03408-w</doi><tpages>4</tpages><orcidid>https://orcid.org/0009-0003-9845-0260</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 0028-3940
ispartof Neuroradiology, 2024-09, Vol.66 (9), p.1577-1580
issn 0028-3940
1432-1920
1432-1920
language eng
recordid cdi_proquest_miscellaneous_3071514267
source Springer Nature
subjects Ataxia
Atrophy
Autopsies
Autopsy
Case Report
Cavitation
Communication
Consent
Diplopia
Etiology
Females
Histopathology
Imaging
Keyholes
Medical imaging
Medicine
Medicine & Public Health
Neurodegenerative diseases
Neuroimaging
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Ophthalmoplegia
Patients
Radiology
Stroke
title Keyhole Aqueduct Syndrome
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T15%3A16%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Keyhole%20Aqueduct%20Syndrome&rft.jtitle=Neuroradiology&rft.au=Zak,%20Imad&rft.date=2024-09-01&rft.volume=66&rft.issue=9&rft.spage=1577&rft.epage=1580&rft.pages=1577-1580&rft.issn=0028-3940&rft.eissn=1432-1920&rft_id=info:doi/10.1007/s00234-024-03408-w&rft_dat=%3Cproquest_cross%3E3092483591%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c256t-23a0e9e76b9e93f752895be29fea01c21e67ce6c76f28b93ef7182d7956f94763%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3092483591&rft_id=info:pmid/38910174&rfr_iscdi=true