Chikungunya fever's chromatic chronicle: a kaleidoscope of pigmentary alterations

Chikungunya fever (CKF), a neglected tropical disease caused by the chikungunya virus, manifests with skin pigmentary changes in a significant portion of people. A myriad of pigmentary alterations in individuals with CKF have been documented in the literature. This review highlights the pathogenesis...

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Bibliographic Details
Published in:Clinical and experimental dermatology 2024-11, Vol.49 (12), p.1489-1495
Main Authors: Palaniappan, Vijayasankar, Gopinath, Hima, Karthikeyan, Kaliaperumal
Format: Article
Language:English
Subjects:
Chikungunya Fever - complications
Chikungunya Fever - diagnosis
Chikungunya virus - isolation & purification
Child
Humans
Pigmentation Disorders - diagnosis
Pigmentation Disorders - etiology
Pigmentation Disorders - pathology
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Summary:Chikungunya fever (CKF), a neglected tropical disease caused by the chikungunya virus, manifests with skin pigmentary changes in a significant portion of people. A myriad of pigmentary alterations in individuals with CKF have been documented in the literature. This review highlights the pathogenesis, clinical features, histopathology, diagnosis and treatment of CKF-associated pigmentation. Notable presentations include the 'Chik sign' often seen in neonates and children. Treatment involves reassurance and topical agents for persistent pigmentation. Understanding these pigmentary changes is crucial for accurate diagnosis and management, facilitating improved patient outcomes. Further research is warranted to fully elucidate the underlying mechanisms and optimize therapeutic strategies.
ISSN:0307-6938
1365-2230
1365-2230
DOI:10.1093/ced/llae242