Dispersal history of SARS‐CoV‐2 in Galicia, Spain

• Published in: Journal of medical virology 2024-07, Vol.96 (7), p.e29773-n/a
• Main Authors: Gallego‐García, Pilar, Estévez‐Gómez, Nuria, De Chiara, Loretta, Alvariño, Pilar, Juiz‐González, Pedro M., Torres‐Beceiro, Isabel, Poza, Margarita, Vallejo, Juan A., Rumbo‐Feal, Soraya, Conde‐Pérez, Kelly, Aja‐Macaya, Pablo, Ladra, Susana, Moreno‐Flores, Antonio, Gude‐González, María J., Coira, Amparo, Aguilera, Antonio, Costa‐Alcalde, José J., Trastoy, Rocío, Barbeito‐Castiñeiras, Gema, García‐Souto, Daniel, Tubio, José M. C., Trigo‐Daporta, Matilde, Camacho‐Zamora, Pablo, Costa, Juan García, González‐Domínguez, María, Canoura‐Fernández, Luis, Glez‐Peña, Daniel, Pérez‐Castro, Sonia, Cabrera, Jorge J., Daviña‐Núñez, Carlos, Godoy‐Diz, Montserrat, Treinta‐Álvarez, Ana Belén, Veiga, Maria Isabel, Sousa, João Carlos, Osório, Nuno S., Comas, Iñaki, González‐Candelas, Fernando, Hong, Samuel L., Bollen, Nena, Dellicour, Simon, Baele, Guy, Suchard, Marc A., Lemey, Philippe, Agulla, Andrés, Bou, Germán, Alonso‐García, Pilar, Pérez‐del‐Molino, María Luisa, García‐Campello, Marta, Paz‐Vidal, Isabel, Regueiro, Benito, Posada, David
• Format: Article
• Language: English
• Subjects: Coronaviruses; COVID-19; COVID-19 - epidemiology; COVID-19 - transmission; COVID-19 - virology; Dispersal; Genome, Viral; Genomic analysis; Humans; Pandemics; Phylogeny; phylogeography; Public health; SARS-CoV-2 - genetics; SARS‐CoV‐2; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Spain - epidemiology; variants of concern; Viral diseases
• ISSN: 0146-6615; 1096-9071; 1096-9071
• DOI: 10.1002/jmv.29773

The dynamics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) transmission are influenced by a variety of factors, including social restrictions and the emergence of distinct variants. In this study, we delve into the origins and dissemination of the Alpha, Delta, and Omicron‐BA.1 variants of concern in Galicia, northwest Spain. For this, we leveraged genomic data collected by the EPICOVIGAL Consortium and from the GISAID database, along with mobility information from other Spanish regions and foreign countries. Our analysis indicates that initial introductions during the Alpha phase were predominantly from other Spanish regions and France. However, as the pandemic progressed, introductions from Portugal and the United States became increasingly significant. The number of detected introductions varied from 96 and 101 for Alpha and Delta to 39 for Omicron‐BA.1. Most of these introductions left a low number of descendants (