Does an untreated peri‐implant dehiscence defect affect the progression of peri‐implantitis?: A preclinical in vivo experimental study

• Published in: Clinical oral implants research 2024-11, Vol.35 (11), p.1373-1381
• Main Authors: Song, Young Woo, Park, Jin‐Young, Na, Ji‐Yeong, Kwon, Yoon‐Hee, Cha, Jae‐Kook, Jung, Ui‐Won, Thoma, Daniel S., Jung, Ronald E.
• Format: Article
• Language: English
• Subjects: Alveolar Bone Loss - diagnostic imaging; Alveolar Bone Loss - etiology; Alveolar Bone Loss - pathology; animal experiment; Animals; Bone implants; Bone resorption; Defects; Dehiscence; dehiscence defect; dental implant; Dental Implantation, Endosseous - methods; Dental implants; Dental Implants - adverse effects; Dental materials; Dental Plaque; Dental prosthetics; Disease Models, Animal; Disease Progression; Dogs; Histology; In vivo methods and tests; Male; Maxilla; Maxilla - diagnostic imaging; Maxilla - surgery; micro‐computed tomography; Peri-Implantitis - etiology; Peri-Implantitis - pathology; peri‐implantitis; Random Allocation; Root resorption; Surgical Wound Dehiscence - etiology; Transplants & implants
• ISSN: 0905-7161; 1600-0501; 1600-0501
• DOI: 10.1111/clr.14324

Objective To investigate the early impact of plaque accumulation in a buccal dehiscence defect on peri‐implant marginal bone resorption. Materials and Methods In six male Mongrel dogs, four dental implants were placed in the posterior maxilla on both sides (two implants per side). Based on the group allocation, each implant was randomly assigned to one of the following four groups to decide whether buccal dehiscence defect was prepared and whether silk ligation was applied at 8 weeks post‐implant placement for peri‐implantitis induction: UC (no defect without ligation); UD (defect without ligation); LC (no defect with ligation); and LD (defect with ligation) groups. Eight weeks after disease induction, the outcomes from radiographic and histologic analyses were statistically analyzed (p