Loading…
Impact of passive ultrasonic irrigation on the outcome of non-surgical root canal treatment: a systematic review and meta-analysis of randomized clinical trials
Objective This systematic review aimed to assess the impact of Passive Ultrasonic Irrigation on the periapical healing rate of primary root canal treatment compared to conventional syringe irrigation. Methods Registered a priori in the PROSPERO database, this review was conducted by two independent...
Saved in:
Published in: | Evidence-based dentistry 2024-12, Vol.25 (4), p.212-213 |
---|---|
Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | |
---|---|
cites | cdi_FETCH-LOGICAL-c326t-56f6e6e761056df864d59e0afc85d26fc2e458f674ecf73b9c3707184afce9393 |
container_end_page | 213 |
container_issue | 4 |
container_start_page | 212 |
container_title | Evidence-based dentistry |
container_volume | 25 |
creator | Gobbo, Leandro Bueno de Araújo, Lucas Peixoto Vieira, Walbert de Andrade de-Jesus-Soares, Adriana de Almeida, José Flávio Affonso Ferraz, Caio Cezar Randi |
description | Objective
This systematic review aimed to assess the impact of Passive Ultrasonic Irrigation on the periapical healing rate of primary root canal treatment compared to conventional syringe irrigation.
Methods
Registered a priori in the PROSPERO database, this review was conducted by two independent reviewers who performed an electronic search up to December 2023. The search included databases such as MEDLINE (PubMed), Scopus, Web of Science, Embase, LILACS, and the Cochrane Library, as well as grey literature. We included randomized clinical trials (RCTs) that focused on patients undergoing primary root canal treatments. The study compared intervention groups using PUI with control groups that did not use activation techniques. Periapical healing was assessed over follow-up periods of at least six months, utilizing either periapical radiographs or cone-beam computed tomography. To synthesize the findings, a meta-analysis and trial sequence analysis were conducted, employing the Relative Risk as the measure of effect, with a 95% confidence interval. The GRADE approach was utilized to assess the certainty of the evidence.
Results
The meta-analysis incorporated three RCTs, involving 474 patients (501 teeth). The analysis revealed that PUI led to a higher rate of periapical healing compared to CSI (Relative Risk: 1.10; 95% Confidence Interval: 1.01-1.21, I² = 0%), with moderate certainty of evidence.
Conclusions
Despite the limited number of high-quality RCTs, the findings showed a positive impact of PUI on periapical healing rates in primary root canal treatments, in comparison to CSI.
Register
CRD42021290894. |
doi_str_mv | 10.1038/s41432-024-01033-3 |
format | article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3074726802</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3074726802</sourcerecordid><originalsourceid>FETCH-LOGICAL-c326t-56f6e6e761056df864d59e0afc85d26fc2e458f674ecf73b9c3707184afce9393</originalsourceid><addsrcrecordid>eNp9kcuKFTEQhhtRnHH0BVxIwI2baO7pdieDl4EBN7oOmXTlmKGTHJP0DMen8VFNzxkVXAgFVVR99YfUPwzPKXlNCR_fVEEFZ5gwgUlvcMwfDKdUaIWlEOrhVqs-JmI6GZ7Uek0I0ZrIx8MJHydJlaKnw8-LuLeuoezR3tYabgCtSyu25hQcCqWEnW0hJ9SjfQOU1-ZyhI1POeG6ll1wdkEl54acTb1sBWyLkNpbZFE91AaxSzhU4CbALbJpRhGaxRt8qKFuWqV3cww_YEZuCelOspVgl_p0eOR7gmf3-Wz4-uH9l_NP-PLzx4vzd5fYcaYalsorUKAVJVLNflRilhMQ690oZ6a8YyDk6JUW4LzmV5Pjmmg6ik7AxCd-Nrw66u5L_r5CbSaG6mBZbIK8VsOJFpqpkbCOvvwHvc5r6b_pVD-_1GwUqlPsSLmSay3gzb6EaMvBUGI2_8zRP9P9M3f-Gd6XXtxLr1cR5j8rvw3rAD8CtY_SDsrft_8j-wvHuKjq</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3147572846</pqid></control><display><type>article</type><title>Impact of passive ultrasonic irrigation on the outcome of non-surgical root canal treatment: a systematic review and meta-analysis of randomized clinical trials</title><source>Springer Nature</source><creator>Gobbo, Leandro Bueno ; de Araújo, Lucas Peixoto ; Vieira, Walbert de Andrade ; de-Jesus-Soares, Adriana ; de Almeida, José Flávio Affonso ; Ferraz, Caio Cezar Randi</creator><creatorcontrib>Gobbo, Leandro Bueno ; de Araújo, Lucas Peixoto ; Vieira, Walbert de Andrade ; de-Jesus-Soares, Adriana ; de Almeida, José Flávio Affonso ; Ferraz, Caio Cezar Randi</creatorcontrib><description>Objective
This systematic review aimed to assess the impact of Passive Ultrasonic Irrigation on the periapical healing rate of primary root canal treatment compared to conventional syringe irrigation.
Methods
Registered a priori in the PROSPERO database, this review was conducted by two independent reviewers who performed an electronic search up to December 2023. The search included databases such as MEDLINE (PubMed), Scopus, Web of Science, Embase, LILACS, and the Cochrane Library, as well as grey literature. We included randomized clinical trials (RCTs) that focused on patients undergoing primary root canal treatments. The study compared intervention groups using PUI with control groups that did not use activation techniques. Periapical healing was assessed over follow-up periods of at least six months, utilizing either periapical radiographs or cone-beam computed tomography. To synthesize the findings, a meta-analysis and trial sequence analysis were conducted, employing the Relative Risk as the measure of effect, with a 95% confidence interval. The GRADE approach was utilized to assess the certainty of the evidence.
Results
The meta-analysis incorporated three RCTs, involving 474 patients (501 teeth). The analysis revealed that PUI led to a higher rate of periapical healing compared to CSI (Relative Risk: 1.10; 95% Confidence Interval: 1.01-1.21, I² = 0%), with moderate certainty of evidence.
Conclusions
Despite the limited number of high-quality RCTs, the findings showed a positive impact of PUI on periapical healing rates in primary root canal treatments, in comparison to CSI.
Register
CRD42021290894.</description><identifier>ISSN: 1462-0049</identifier><identifier>ISSN: 1476-5446</identifier><identifier>EISSN: 1476-5446</identifier><identifier>DOI: 10.1038/s41432-024-01033-3</identifier><identifier>PMID: 38951661</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/698/3008/3010 ; 692/700/3032/3123/3119 ; Clinical trials ; Computed tomography ; Dentistry ; Endodontics ; Evidence-Based Dentistry ; Humans ; Lavage ; Medicine ; Meta-analysis ; Patients ; Randomized Controlled Trials as Topic ; Root Canal Irrigants - administration & dosage ; Root Canal Irrigants - therapeutic use ; Root Canal Therapy - methods ; Root canals ; Sequence analysis ; Systematic review ; Therapeutic Irrigation - methods ; Treatment Outcome ; Ultrasonics</subject><ispartof>Evidence-based dentistry, 2024-12, Vol.25 (4), p.212-213</ispartof><rights>The Author(s), under exclusive licence to British Dental Association 2024 Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2024. The Author(s), under exclusive licence to British Dental Association.</rights><rights>Copyright Nature Publishing Group Dec 2024</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c326t-56f6e6e761056df864d59e0afc85d26fc2e458f674ecf73b9c3707184afce9393</cites><orcidid>0000-0003-2893-1416</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38951661$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gobbo, Leandro Bueno</creatorcontrib><creatorcontrib>de Araújo, Lucas Peixoto</creatorcontrib><creatorcontrib>Vieira, Walbert de Andrade</creatorcontrib><creatorcontrib>de-Jesus-Soares, Adriana</creatorcontrib><creatorcontrib>de Almeida, José Flávio Affonso</creatorcontrib><creatorcontrib>Ferraz, Caio Cezar Randi</creatorcontrib><title>Impact of passive ultrasonic irrigation on the outcome of non-surgical root canal treatment: a systematic review and meta-analysis of randomized clinical trials</title><title>Evidence-based dentistry</title><addtitle>Evid Based Dent</addtitle><addtitle>Evid Based Dent</addtitle><description>Objective
This systematic review aimed to assess the impact of Passive Ultrasonic Irrigation on the periapical healing rate of primary root canal treatment compared to conventional syringe irrigation.
Methods
Registered a priori in the PROSPERO database, this review was conducted by two independent reviewers who performed an electronic search up to December 2023. The search included databases such as MEDLINE (PubMed), Scopus, Web of Science, Embase, LILACS, and the Cochrane Library, as well as grey literature. We included randomized clinical trials (RCTs) that focused on patients undergoing primary root canal treatments. The study compared intervention groups using PUI with control groups that did not use activation techniques. Periapical healing was assessed over follow-up periods of at least six months, utilizing either periapical radiographs or cone-beam computed tomography. To synthesize the findings, a meta-analysis and trial sequence analysis were conducted, employing the Relative Risk as the measure of effect, with a 95% confidence interval. The GRADE approach was utilized to assess the certainty of the evidence.
Results
The meta-analysis incorporated three RCTs, involving 474 patients (501 teeth). The analysis revealed that PUI led to a higher rate of periapical healing compared to CSI (Relative Risk: 1.10; 95% Confidence Interval: 1.01-1.21, I² = 0%), with moderate certainty of evidence.
Conclusions
Despite the limited number of high-quality RCTs, the findings showed a positive impact of PUI on periapical healing rates in primary root canal treatments, in comparison to CSI.
Register
CRD42021290894.</description><subject>692/698/3008/3010</subject><subject>692/700/3032/3123/3119</subject><subject>Clinical trials</subject><subject>Computed tomography</subject><subject>Dentistry</subject><subject>Endodontics</subject><subject>Evidence-Based Dentistry</subject><subject>Humans</subject><subject>Lavage</subject><subject>Medicine</subject><subject>Meta-analysis</subject><subject>Patients</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Root Canal Irrigants - administration & dosage</subject><subject>Root Canal Irrigants - therapeutic use</subject><subject>Root Canal Therapy - methods</subject><subject>Root canals</subject><subject>Sequence analysis</subject><subject>Systematic review</subject><subject>Therapeutic Irrigation - methods</subject><subject>Treatment Outcome</subject><subject>Ultrasonics</subject><issn>1462-0049</issn><issn>1476-5446</issn><issn>1476-5446</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kcuKFTEQhhtRnHH0BVxIwI2baO7pdieDl4EBN7oOmXTlmKGTHJP0DMen8VFNzxkVXAgFVVR99YfUPwzPKXlNCR_fVEEFZ5gwgUlvcMwfDKdUaIWlEOrhVqs-JmI6GZ7Uek0I0ZrIx8MJHydJlaKnw8-LuLeuoezR3tYabgCtSyu25hQcCqWEnW0hJ9SjfQOU1-ZyhI1POeG6ll1wdkEl54acTb1sBWyLkNpbZFE91AaxSzhU4CbALbJpRhGaxRt8qKFuWqV3cww_YEZuCelOspVgl_p0eOR7gmf3-Wz4-uH9l_NP-PLzx4vzd5fYcaYalsorUKAVJVLNflRilhMQ690oZ6a8YyDk6JUW4LzmV5Pjmmg6ik7AxCd-Nrw66u5L_r5CbSaG6mBZbIK8VsOJFpqpkbCOvvwHvc5r6b_pVD-_1GwUqlPsSLmSay3gzb6EaMvBUGI2_8zRP9P9M3f-Gd6XXtxLr1cR5j8rvw3rAD8CtY_SDsrft_8j-wvHuKjq</recordid><startdate>20241201</startdate><enddate>20241201</enddate><creator>Gobbo, Leandro Bueno</creator><creator>de Araújo, Lucas Peixoto</creator><creator>Vieira, Walbert de Andrade</creator><creator>de-Jesus-Soares, Adriana</creator><creator>de Almeida, José Flávio Affonso</creator><creator>Ferraz, Caio Cezar Randi</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2893-1416</orcidid></search><sort><creationdate>20241201</creationdate><title>Impact of passive ultrasonic irrigation on the outcome of non-surgical root canal treatment: a systematic review and meta-analysis of randomized clinical trials</title><author>Gobbo, Leandro Bueno ; de Araújo, Lucas Peixoto ; Vieira, Walbert de Andrade ; de-Jesus-Soares, Adriana ; de Almeida, José Flávio Affonso ; Ferraz, Caio Cezar Randi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-56f6e6e761056df864d59e0afc85d26fc2e458f674ecf73b9c3707184afce9393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>692/698/3008/3010</topic><topic>692/700/3032/3123/3119</topic><topic>Clinical trials</topic><topic>Computed tomography</topic><topic>Dentistry</topic><topic>Endodontics</topic><topic>Evidence-Based Dentistry</topic><topic>Humans</topic><topic>Lavage</topic><topic>Medicine</topic><topic>Meta-analysis</topic><topic>Patients</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Root Canal Irrigants - administration & dosage</topic><topic>Root Canal Irrigants - therapeutic use</topic><topic>Root Canal Therapy - methods</topic><topic>Root canals</topic><topic>Sequence analysis</topic><topic>Systematic review</topic><topic>Therapeutic Irrigation - methods</topic><topic>Treatment Outcome</topic><topic>Ultrasonics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gobbo, Leandro Bueno</creatorcontrib><creatorcontrib>de Araújo, Lucas Peixoto</creatorcontrib><creatorcontrib>Vieira, Walbert de Andrade</creatorcontrib><creatorcontrib>de-Jesus-Soares, Adriana</creatorcontrib><creatorcontrib>de Almeida, José Flávio Affonso</creatorcontrib><creatorcontrib>Ferraz, Caio Cezar Randi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Evidence-based dentistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gobbo, Leandro Bueno</au><au>de Araújo, Lucas Peixoto</au><au>Vieira, Walbert de Andrade</au><au>de-Jesus-Soares, Adriana</au><au>de Almeida, José Flávio Affonso</au><au>Ferraz, Caio Cezar Randi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of passive ultrasonic irrigation on the outcome of non-surgical root canal treatment: a systematic review and meta-analysis of randomized clinical trials</atitle><jtitle>Evidence-based dentistry</jtitle><stitle>Evid Based Dent</stitle><addtitle>Evid Based Dent</addtitle><date>2024-12-01</date><risdate>2024</risdate><volume>25</volume><issue>4</issue><spage>212</spage><epage>213</epage><pages>212-213</pages><issn>1462-0049</issn><issn>1476-5446</issn><eissn>1476-5446</eissn><abstract>Objective
This systematic review aimed to assess the impact of Passive Ultrasonic Irrigation on the periapical healing rate of primary root canal treatment compared to conventional syringe irrigation.
Methods
Registered a priori in the PROSPERO database, this review was conducted by two independent reviewers who performed an electronic search up to December 2023. The search included databases such as MEDLINE (PubMed), Scopus, Web of Science, Embase, LILACS, and the Cochrane Library, as well as grey literature. We included randomized clinical trials (RCTs) that focused on patients undergoing primary root canal treatments. The study compared intervention groups using PUI with control groups that did not use activation techniques. Periapical healing was assessed over follow-up periods of at least six months, utilizing either periapical radiographs or cone-beam computed tomography. To synthesize the findings, a meta-analysis and trial sequence analysis were conducted, employing the Relative Risk as the measure of effect, with a 95% confidence interval. The GRADE approach was utilized to assess the certainty of the evidence.
Results
The meta-analysis incorporated three RCTs, involving 474 patients (501 teeth). The analysis revealed that PUI led to a higher rate of periapical healing compared to CSI (Relative Risk: 1.10; 95% Confidence Interval: 1.01-1.21, I² = 0%), with moderate certainty of evidence.
Conclusions
Despite the limited number of high-quality RCTs, the findings showed a positive impact of PUI on periapical healing rates in primary root canal treatments, in comparison to CSI.
Register
CRD42021290894.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>38951661</pmid><doi>10.1038/s41432-024-01033-3</doi><tpages>2</tpages><orcidid>https://orcid.org/0000-0003-2893-1416</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1462-0049 |
ispartof | Evidence-based dentistry, 2024-12, Vol.25 (4), p.212-213 |
issn | 1462-0049 1476-5446 1476-5446 |
language | eng |
recordid | cdi_proquest_miscellaneous_3074726802 |
source | Springer Nature |
subjects | 692/698/3008/3010 692/700/3032/3123/3119 Clinical trials Computed tomography Dentistry Endodontics Evidence-Based Dentistry Humans Lavage Medicine Meta-analysis Patients Randomized Controlled Trials as Topic Root Canal Irrigants - administration & dosage Root Canal Irrigants - therapeutic use Root Canal Therapy - methods Root canals Sequence analysis Systematic review Therapeutic Irrigation - methods Treatment Outcome Ultrasonics |
title | Impact of passive ultrasonic irrigation on the outcome of non-surgical root canal treatment: a systematic review and meta-analysis of randomized clinical trials |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T23%3A33%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Impact%20of%20passive%20ultrasonic%20irrigation%20on%20the%20outcome%20of%20non-surgical%20root%20canal%20treatment:%20a%20systematic%20review%20and%20meta-analysis%20of%20randomized%20clinical%20trials&rft.jtitle=Evidence-based%20dentistry&rft.au=Gobbo,%20Leandro%20Bueno&rft.date=2024-12-01&rft.volume=25&rft.issue=4&rft.spage=212&rft.epage=213&rft.pages=212-213&rft.issn=1462-0049&rft.eissn=1476-5446&rft_id=info:doi/10.1038/s41432-024-01033-3&rft_dat=%3Cproquest_cross%3E3074726802%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c326t-56f6e6e761056df864d59e0afc85d26fc2e458f674ecf73b9c3707184afce9393%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3147572846&rft_id=info:pmid/38951661&rfr_iscdi=true |