Paediatric bipolar disorder with Duchenne muscular dystrophy: A case report

Duchenne muscular dystrophy (DMD) is one of the most severe forms of inherited muscular dystrophies. It is caused by a mutation in the dystrophin gene, leading to progressive muscular degeneration and weakness. It is inherited as an X-linked recessive trait, mostly located on chromosome Xp21; howeve...

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Bibliographic Details
Published in:East Asian archives of psychiatry 2024-06, Vol.34 (2), p.43-44
Main Authors: Mallik, S, Ranjan, R, Gourav, K, Aggarwal, K
Format: Article
Language:English
Subjects:
Bipolar disorder
Bipolar Disorder - complications
Bipolar Disorder - diagnosis
Bipolar Disorder - psychology
Child
Child psychopathology
Duchenne muscular dystrophy
Dystrophin
GABA
Genetic aspects
Humans
Male
Muscular dystrophy
Muscular Dystrophy, Duchenne - complications
Mutation
Neurophysiology
Neurosciences
Patients
Pediatrics
Psychiatry
Sleep
Surveillance
Utrophin
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Summary:Duchenne muscular dystrophy (DMD) is one of the most severe forms of inherited muscular dystrophies. It is caused by a mutation in the dystrophin gene, leading to progressive muscular degeneration and weakness. It is inherited as an X-linked recessive trait, mostly located on chromosome Xp21; however, approximately 30% of cases are de novo mutations. Mutations lead to limited production of the dystrophin protein, which results in loss of myofibres and progressive replacement of muscle with connective tissue and fat. Children with DMD have difficulty walking, whereas increased steroid intake can result in depressed mood or attention deficit hyperactivity disorder.
ISSN:2078-9947
2224-7041
2224-7041
DOI:10.12809/eaap2348