Successful pre-surgical treatment with carboplatin and gemcitabine chemotherapy for a patient with muscle-invasive bladder cancer and severe renal dysfunction

Radical cystectomy is the standard treatment for muscle-invasive bladder cancer, and pre-surgical treatment can improve survival. Carboplatin and gemcitabine chemotherapy is considered an effective, safe treatment for patients ineligible for cisplatin-based chemotherapy owing to reduced renal functi...

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Bibliographic Details
Published in:International cancer conference journal 2024-07, Vol.13 (3), p.230-234
Main Authors: Torii, Shota, Narita, Tomoya, Homma, Takamasa, Kinoshita, Teruhisa, Torii-Goto, Aya, Esaki, Hideki, Sakakibara, Takashi, Kondo, Atsuya, Takimoto, Norio
Format: Article
Language:English
Subjects:
Abdomen
Acidosis
Bladder cancer
Blood
Blood platelets
Carboplatin
Case Report - Chemotherapy
Chemotherapy
Cisplatin
Colony-stimulating factor
Creatinine
Cytokeratin
Drug dosages
Gemcitabine
Glomerular filtration rate
Granulocyte colony-stimulating factor
Granulocytes
Hematuria
Hemodialysis
Hemoglobin
Hyperkalemia
Invasiveness
Leukocytes
Leukocytes (granulocytic)
Lymphatic system
Magnetic resonance imaging
Medical prognosis
Medicine
Medicine & Public Health
Metabolism
Metastasis
Neutropenia
Neutrophils
Oncology
Patients
Renal function
Robotic surgery
Surgical Oncology
Thrombocytopenia
Tumors
Urological surgery
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Description
Summary:Radical cystectomy is the standard treatment for muscle-invasive bladder cancer, and pre-surgical treatment can improve survival. Carboplatin and gemcitabine chemotherapy is considered an effective, safe treatment for patients ineligible for cisplatin-based chemotherapy owing to reduced renal function. However, there is limited evidence on pre-surgical treatment with carboplatin and gemcitabine chemotherapy with glomerular filtration rates 
ISSN:2192-3183
2192-3183
DOI:10.1007/s13691-024-00667-5