68Ga-NODAGA-Exendin-4 PET/CT Findings in a Case of Metastatic Insulinoma With Refractory Hypoglycemia Controlled by 90Y Transarterial Radioembolization

Metastatic insulinomas can cause recurrent hypoglycemia requiring continuous IV glucose infusion. Various medical and chemotherapeutic treatment options are used to reduce the patient's risk of death due to hypoglycemia. Treatment-resistant hepatic metastatic insulinomas may benefit clinically...

Full description

Saved in:
Bibliographic Details
Published in:Clinical nuclear medicine 2024-08, Vol.49 (8), p.e392-e393
Main Authors: Şahin, Rahime, Rakıcı, İbrahim Taşkın, Baloğlu, Mehmet Can, Şahin, Ömer Faruk, Çermik, Tevfik Fikret
Format: Article
Language:English
Subjects:
Acetates
Embolization, Therapeutic
Exenatide
Gallium Radioisotopes
Heterocyclic Compounds, 1-Ring - therapeutic use
Humans
Hypoglycemia
Insulinoma - diagnostic imaging
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - radiotherapy
Liver Neoplasms - secondary
Male
Middle Aged
Neoplasm Metastasis
Pancreatic Neoplasms - diagnostic imaging
Pancreatic Neoplasms - radiotherapy
Positron Emission Tomography Computed Tomography
Yttrium Radioisotopes - therapeutic use
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Metastatic insulinomas can cause recurrent hypoglycemia requiring continuous IV glucose infusion. Various medical and chemotherapeutic treatment options are used to reduce the patient's risk of death due to hypoglycemia. Treatment-resistant hepatic metastatic insulinomas may benefit clinically from 90Y transarterial radioembolization therapy. In this case, we present a case of liver metastatic insulinoma that achieved clinical improvement after 2 cycles of 90Y microspheres transarterial radioembolization, and the presence of active metastases was demonstrated with 68Ga-NODAGA-exendin-4 PET/CT imaging.
ISSN:0363-9762
1536-0229
1536-0229
DOI:10.1097/RLU.0000000000005266