Effect of prenatal glucocorticoid therapy on hearing screening in premature infants

• Published in: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery head, and neck surgery, 2024-07, Vol.38 (7), p.618
• Main Authors: Li, Li, Wei, Lu, Chen, Zhangzhen, Pan, Lingxin, Li, Luquan, Song, Yan
• Format: Article
• Language: Chinese
• Subjects: Dexamethasone - administration & dosage; Dexamethasone - therapeutic use; Female; Gestational Age; Glucocorticoids - administration & dosage; Glucocorticoids - adverse effects; Glucocorticoids - therapeutic use; Hearing Tests; Humans; Infant, Newborn; Infant, Premature; Male; Neonatal Screening - methods; Pregnancy; Prenatal Care - methods; Retrospective Studies
• ISSN: 2096-7993
• DOI: 10.13201/j.issn.2096-7993.2024.07.012

To explore the effect of prenatal glucocorticoids therapy on hearing screening in premature infants Data of 693 preterm infants with gestational age of 24-34+6weeks admitted to theJiangxi Maternal and Child Health Hospital within 24 h after birth from June 2022 to June 2023 were retrospectively analyzed. The infants were divided into the DXM group （544 cases） and the non-DXM group （149 cases） based on whether dexamethasone （DXM） was administered prenatally. General data of preterm infants and parturients in two groups were compared, and the effects of different doses and timing of DXM on hearing screening were analyzed. In the terms of preliminary hearing screening. the pass rate of initial hearing screening in DXM group was significantly higher than that in non-DXM group（53.9% vs 35.6%）, with statistical significance（