Laparoscopic-Assisted Colonic Derotation in Patients With Hirschsprung Disease

• Published in: Journal of pediatric surgery 2024-10, Vol.59 (10), p.161600, Article 161600
• Main Authors: Srinivas, Shruthi, Ahmad, Hira, Knaus, Maria E., Pruitt, Liese C.C., Jimenez, Alberta Negri, Read, Megan, Liaqat, Naeem, Langer, Jacob C., Levitt, Marc A., Diefenbach, Karen A., Halaweish, Ihab, Gasior, Alessandra C., Wood, Richard J.
• Format: Article
• Language: English
• Subjects: Anastomosis, Surgical - methods; Child, Preschool; Colon - blood supply; Colon - surgery; Female; Hirschsprung Disease - surgery; Humans; Infant; Laparoscopy - methods; Long-segment Hirschsprung disease; Male; Postoperative Complications - epidemiology; Postoperative Complications - etiology; Postoperative Complications - prevention & control; Pull-through; Retrospective Studies; Surgical technique; Treatment Outcome
• ISSN: 0022-3468; 1531-5037; 1531-5037
• DOI: 10.1016/j.jpedsurg.2024.06.009

Children with Hirschsprung disease (HSCR) proximal to the splenic flexure or those needing a redo pull-through (PT) are at risk for tension and ischemia of the PT which could result in leak, stricture, or loss of ganglionated bowel. Colonic derotation is a technique used to minimize tension and avoid duodenal obstruction. The aim of this study was to describe this technique and outcomes in a series of patients requiring this intervention. All patients underwent initial diversion and colonic mapping. The derotation procedure involves mobilization of the remaining colon, counterclockwise rotation via the stoma closure site, placement of the pull through (the right colon) lying on the right of the pelvis, and ligation of the middle colic artery with preservation of the marginal branch running from the ileocolic artery. This maneuver prevents compression of the duodenum by the mesenteric vessels and allows for an isoperistaltic, tension-free anastomosis. Intraoperative indocyanine green fluorescence angiography (ICG-FA) was utilized in many of the cases to map the blood supply of the pull-through colon. We reviewed outcomes for all children with HSCR who underwent colonic derotation from 2014 to 2023. Descriptive statistics were performed. There were 37 children included. Most were male (67.5%) with the original transition zone proximal to the rectosigmoid (81.1%). The median age at PT was 9.3 months [6.1–39.7]. Median operative time was 6.6 h [4.9–7.4] and 19 cases (51.4%) used ICG-FA. Most children had no 30-day postoperative complications (67.6%); in those who did develop complications, readmissions for electrolyte imbalance was most common (50.0%). There were zero cases of anastomotic leak at PT anastomosis. At long-term follow up, median 4.4 years [2.3–7.0], three children (8.1%) developed an anastomotic stricture, all were amenable to anal dilation, and five experienced episodes of enterocolitis (14.7%). Most children had between 1 and 4 stools per day (58.8%). Colonic derotation is a useful strategy to ensure well-perfused colonic length, protect the marginal artery blood supply, avoid duodenal compression, and ensure a tension-free anastomosis with minimal complications. Original research, retrospective cohort. III. •Patients with Hirschsprung disease with proximal transition zones or need for redo operations in which the right colon must be used for PT require astute operative planning to maximize colonic salvage and ensure viability of the coloanal a