Programmable DNA rearrangements using bridge RNAs

Two studies in Nature reveal the mechanistic and structural properties of a family of mobile genetic elements that can be reprogrammed to engineer genome modifications.

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Bibliographic Details
Published in:Nature reviews. Genetics 2024-09, Vol.25 (9), p.599-599
Main Author: Ertl, Henry
Format: Article
Language:English
Subjects:
631/337/384
631/553/2690
Agriculture
Animal Genetics and Genomics
Biomedical and Life Sciences
Biomedicine
Cancer Research
DNA - genetics
Gene Function
Gene Rearrangement
Human Genetics
Humans
Research Highlight
RNA - genetics
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Description
Summary:Two studies in Nature reveal the mechanistic and structural properties of a family of mobile genetic elements that can be reprogrammed to engineer genome modifications.
ISSN:1471-0056
1471-0064
1471-0064
DOI:10.1038/s41576-024-00763-5