Neoadjuvant Chemotherapy in Breast Cancer: Evaluation of the Impact on Surgical Outcomes and Prognosis

The correlation between TNM staging and histology variations in a sample of patients who underwent neoadjuvant chemotherapy demonstrates a positive impact on both increasing conservative surgery and achieving pCR, resulting in better outcomes in terms of disease-free survival (DFS) and the risk of r...

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Bibliographic Details
Published in:Cancers 2024-06, Vol.16 (13), p.2332
Main Authors: Chiappa, Corrado, Greta, Maltecca, Miriam, Leoni, Ietto, Giuseppe, Inversini, Davide, Ballabio, Andrea, Bonetti, Alice, Mangano, Alberto, Gueli, Rossana, Carcano, Giulio, Rovera, Francesca Angela
Format: Article
Language:English
Subjects:
Breast cancer
Cancer therapies
Chemotherapy
Complications
Disease management
Lumpectomy
Lymphatic system
Mammography
Mastectomy
Medical prognosis
Patients
Postoperative
Prognosis
Response rates
Surgery
Surgical outcomes
Survival
Tumors
Ultrasonic imaging
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Summary:The correlation between TNM staging and histology variations in a sample of patients who underwent neoadjuvant chemotherapy demonstrates a positive impact on both increasing conservative surgery and achieving pCR, resulting in better outcomes in terms of disease-free survival (DFS) and the risk of relapse. Benefits have also been highlighted in terms of cosmetic outcomes, postoperative complications, and psychological benefits. However, the overall outcomes must be evaluated according to the subtype and individual characteristics of the patients.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers16132332