Ceftriaxone Versus Cefazolin Susceptibility as a Surrogate Marker for Cefpodoxime Susceptibility in Enterobacterales

Abstract The Clinical and Laboratory Standards Institute stated that cefpodoxime susceptibility among Enterobacterales can be inferred from cefazolin, but this may overcall cefpodoxime resistance. We report a categorical agreement rate of 64% for cefazolin and 97% for ceftriaxone with cefpodoxime (P...

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Published in:Open forum infectious diseases 2024-07, Vol.11 (7), p.ofae377
Main Authors: Lambert, Kaitlyn V, Demkowicz, Ryan, Murray, Amanda, Howard, Catessa, Slain, Douglas
Format: Article
Language:English
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Summary:Abstract The Clinical and Laboratory Standards Institute stated that cefpodoxime susceptibility among Enterobacterales can be inferred from cefazolin, but this may overcall cefpodoxime resistance. We report a categorical agreement rate of 64% for cefazolin and 97% for ceftriaxone with cefpodoxime (P = .0001). Ceftriaxone appears to be a more useful cefpodoxime surrogate.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofae377