One-year outcomes in COVID-19 and non-COVID-19 intensive care unit survivors

• Published in: Journal of critical care 2024-12, Vol.84, p.154858, Article 154858
• Main Authors: Heesakkers, Hidde, van der Hoeven, Johannes G., Corsten, Stijn, Janssen, Inge, Ewalds, Esther, Simons, Koen S., de Blauw, Maaike, Rettig, Thijs C.D., Jacobs, Crétien, van Santen, Susanne, Slooter, Arjen J.C., van der Woude, Margaretha C.E., Zegers, Marieke, van den Boogaard, Mark
• Format: Article
• Language: English
• Subjects: Aged; Anxiety; Cohort analysis; COVID-19; COVID-19 - epidemiology; COVID-19 - psychology; Critical care outcomes; Critical illness; Depression - epidemiology; Depression - psychology; Female; Frailty; Hospitals; Humans; Illnesses; Intensive care; Intensive Care Units; Likert scale; Male; Middle Aged; Missing data; Pandemics; Patients; Pneumonia; Post traumatic stress disorder; Quality of Life; Questionnaires; Regression analysis; Respiratory distress syndrome; SARS-CoV-2; Survivor; Survivors - psychology
• ISSN: 0883-9441; 1557-8615; 1557-8615
• DOI: 10.1016/j.jcrc.2024.154858

To determine differences in one-year multi-domain health outcomes in COVID-19 and non-COVID-19 intensive care unit (ICU) survivors. Adult ICU survivors treated for COVID-19 were compared to a control group consisting of survivors admitted for respiratory distress due to other causes, i.e. non-COVID-19 ARDS or pneumonia. Occurrence of physical (frailty, fatigue, physical symptoms), mental (anxiety, depression, post-traumatic stress) and cognitive symptoms, and quality of life (QoL) scores were measured, using validated questionnaires, before and one year after ICU treatment. In total, 506 COVID-19 survivors could be compared to 228 non-COVID-19 survivors. At one-year follow-up, COVID-19 ICU survivors had less physical (76.2% vs. 86.9%, p = 0.001) and mental symptoms (32.0% vs. 47.1%, p