Liquorilactobacillus: A Context of the Evolutionary History and Metabolic Adaptation of a Bacterial Genus from Fermentation Liquid Environments

• Published in: Journal of molecular evolution 2024-08, Vol.92 (4), p.467-487
• Main Authors: da Silva Santos, Dayane, Freitas, Nara Suzy Aguiar, de Morais, Marcos Antonio, Mendonça, Allyson Andrade
• Format: Article
• Language: English
• Subjects: Acid resistance; Adaptation; Amino acids; Animal Genetics and Genomics; Antibiotic resistance; Antibiotics; Auxotrophy; Bacillus; Biomedical and Life Sciences; Cell Biology; Evolution; Evolutionary Biology; Evolutionary genetics; Fermentation; Genes; Genomes; Genomic analysis; Lactobacilli; Life Sciences; Microbiology; Original Article; Pattern analysis; Phylogeny; Plant Genetics and Genomics; Plant Sciences; Speciation; Species; Taxa; Trajectory analysis
• ISSN: 0022-2844; 1432-1432; 1432-1432
• DOI: 10.1007/s00239-024-10189-6

In the present work, we carried out a comparative genomic analysis to trace the evolutionary trajectory of the bacterial species that make up the Liquorilactobacillus genus, from the identification of genes and speciation/adaptation mechanisms in their unique characteristics to the identification of the pattern grouping these species. We present phylogenetic relationships between Liquorilactobacillus and related taxa such as Bacillus , basal lactobacilli and Ligilactobacillus , highlighting evolutionary divergences and lifestyle transitions across different taxa. The species of this genus share a core genome of 1023 genes, distributed in all COGs, which made it possible to characterize it as Liquorilactobacillus sensu lato: few amino acid auxotrophy, low genes number for resistance to antibiotics and general and specific cellular reprogramming mechanisms for environmental responses. These species were divided into four clades, with diversity being enhanced mainly by the diversity of genes involved in sugar metabolism. Clade 1 presented lower (