High prevalence and genomic features of multidrug-resistant Salmonella enterica isolated from chilled broiler chicken on retail sale in the United Arab Emirates

Non-typhoidal Salmonella represents a significant global concern for food safety and One Health. Despite the United Arab Emirates (UAE) being a leading consumer of chicken meat globally, there is a lack of comprehensive understanding regarding the prevalence and genomic characteristics of Salmonella...

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Bibliographic Details
Published in:International journal of food microbiology 2024-10, Vol.423, p.110828, Article 110828
Main Authors: Habib, Ihab, Mohamed, Mohamed-Yousif Ibrahim, Lakshmi, Glindya Bhagya, Ghazawi, Akela, Khan, Mushtaq, Abdalla, Afra, Anes, Febin
Format: Article
Language:English
Subjects:
Animals
Anti-Bacterial Agents - pharmacology
Antibiotic resistance
Chicken
Chickens - microbiology
Drug Resistance, Multiple, Bacterial - genetics
Food Contamination - analysis
Food Microbiology
Genome, Bacterial
Genomic characterization
Meat - microbiology
Microbial Sensitivity Tests
Prevalence
Salmonella
Salmonella enterica - drug effects
Salmonella enterica - genetics
Salmonella enterica - isolation & purification
UAE
United Arab Emirates - epidemiology
Whole Genome Sequencing
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Summary:Non-typhoidal Salmonella represents a significant global concern for food safety and One Health. Despite the United Arab Emirates (UAE) being a leading consumer of chicken meat globally, there is a lack of comprehensive understanding regarding the prevalence and genomic characteristics of Salmonella within the country. This study aims to address this gap by conducting a thorough analysis of Salmonella prevalence, antimicrobial resistance, and genomic profiles of isolates obtained from whole broiler carcasses retailed under chilled conditions in the UAE. Our findings reveal that Salmonella was detected in 41.2 % (130/315) of the sampled chilled broiler carcasses, with notable variability observed among samples sourced from six different companies. Phenotypic antimicrobial resistance (AMR) testing, among 105 isolates, highlighted high resistance rates to tetracycline (97.1 %), nalidixic acid (93.3 %), ampicillin (92.4 %), azithromycin (75.2 %), ciprofloxacin (63.8 %), and ceftriaxone (54.3 %). Furthermore, a concerning 99 % (104/105) of the isolates exhibited multidrug resistance. Whole-genome sequencing (WGS) of 60 isolates identified five serovars, with S. infantis/Sequence Type (ST) 32 (55 %) and S. Minnesota/ST-458 (28.3 %) being the most prevalent. WGS analysis unveiled 34 genes associated with antimicrobial resistance, including mcr-1.1 (only in two isolates), conferring resistance to colistin. The two major serovars, Infantis and Minnesota, exhibited significant variation (P-values
ISSN:0168-1605
1879-3460
1879-3460
DOI:10.1016/j.ijfoodmicro.2024.110828