Society for endocrinology guideline for understanding, diagnosing and treating female hypogonadism

• Published in: Clinical endocrinology (Oxford) 2024-11, Vol.101 (5), p.409-442
• Main Authors: Jayasena, Channa N., Devine, Kerri, Barber, Katie, Comninos, Alexander N., Conway, Gerard S., Crown, Anna, Davies, Melanie C., Ewart, Ann, Seal, Leighton J., Smyth, Arlene, Turner, Helen E., Webber, Lisa, Anderson, Richard A., Quinton, Richard
• Format: Article
• Language: English
• Subjects: Endocrine disorders; Endocrinology; Endocrinology - methods; Endocrinology - standards; estrogen; Estrogens; Female; guideline; Humans; Hypogonadism; Hypogonadism - diagnosis; Hypogonadism - therapy; menopause; ovarian insufficiency; Pituitary; Post-menopause; Practice Guidelines as Topic; Primary care; Primary Ovarian Insufficiency - diagnosis; Primary Ovarian Insufficiency - therapy; Reproductive health; Societies, Medical - standards
• ISSN: 0300-0664; 1365-2265; 1365-2265
• DOI: 10.1111/cen.15097

Female hypogonadism (FH) is a relatively common endocrine disorder in women of premenopausal age, but there are significant uncertainties and wide variation in its management. Most current guidelines are monospecialty and only address premature ovarian insufficiency (POI); some allude to management in very brief and general terms, and most rely upon the extrapolation of evidence from the studies relating to physiological estrogen deficiency in postmenopausal women. The Society for Endocrinology commissioned new guidance to provide all care providers with a multidisciplinary perspective on managing patients with all forms of FH. It has been compiled using expertise from Endocrinology, Primary Care, Gynaecology and Reproductive Health practices, with contributions from expert patients and a patient support group, to help clinicians best manage FH resulting from both POI and hypothalamo‐pituitary disorders, whether organic or functional.