Takotsubo cardiomyopathy in a patient with Lynch syndrome

In her family history, her paternal uncle had bowel and stomach cancer and his daughter had bowel and breast cancer. On examination, we found the patient to be unwell and reporting abdominal pain; she was hypotensive with a blood pressure of 92/57 mm Hg—she had managed to drink only small amounts of...

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Bibliographic Details
Published in:The Lancet (British edition) 2024-07, Vol.404 (10449), p.276-276
Main Authors: Hosten, Katia, Kazi, Sayed Irfan, Kardos, Attila
Format: Article
Language:English
Subjects:
Blood clots
Blood pressure
Cancer
Cardiomyopathy
Chemotherapy
Colorectal cancer
Colorectal Neoplasms, Hereditary Nonpolyposis - complications
Echocardiography
Electrocardiography
Female
Gastric cancer
Genetic disorders
Genetics
Heart
Humans
Intestine
Middle Aged
Ostomy
Pain
Takotsubo Cardiomyopathy - complications
Takotsubo Cardiomyopathy - etiology
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Summary:In her family history, her paternal uncle had bowel and stomach cancer and his daughter had bowel and breast cancer. On examination, we found the patient to be unwell and reporting abdominal pain; she was hypotensive with a blood pressure of 92/57 mm Hg—she had managed to drink only small amounts of fluid prior to coming to hospital. The patient's condition stabilised and she reported no further chest pain. 2 weeks later, transthoracic echocardiography showed full recovery of the left ventricular apical dyskinesis, and the ejection fraction had increased from 45% to a range of 55–60% (normal range 50–70%; figure).
ISSN:0140-6736
1474-547X
1474-547X
DOI:10.1016/S0140-6736(24)01262-5