Lipid extract of microalgae Chlorella vulgaris and Arthrospira platensis as a bioactive ingredient

A growing market for seaweed products has emerged in the last 20 years, with microalgae and their extracts representing a source of high-value chemicals. In this study, antioxidative and anti-inflammatory activities of lipid fraction extract from (Chlorella) and (Spirulina) on Normal Human Dermal Fi...

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Published in:Food science and technology international 2024-07, p.10820132241264419
Main Authors: García-Segovia, Purificación, Uribe-Wandurraga, Zaida Natalia, Igual, Marta, Mullor, José Luís, Martínez-Monzó, Javier
Format: Article
Language:English
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Summary:A growing market for seaweed products has emerged in the last 20 years, with microalgae and their extracts representing a source of high-value chemicals. In this study, antioxidative and anti-inflammatory activities of lipid fraction extract from (Chlorella) and (Spirulina) on Normal Human Dermal Fibroblasts (NHDF cells) were evaluated. Treatments with Chlorella and Spirulina lipid extracts in NHDF cells at 0.1, 0.5, and 1% significantly protect UVA-induced damage by decreasing oxidative stress in the form of reactive oxygen species (ROS) but do not display any significant protection from HEV-induced damage. Chlorella or Spirulina lipid extracts at 0.1 and 0.5% display significant anti-inflammatory effects by inhibiting the 2-propanol-induced IL-6 expression on NHDF cells but showed no decrease in TNF-α expression. Chlorella and Spirulina lipid extracts present antioxidant and anti-inflammatory activity on NHDF cells.
ISSN:1082-0132
1532-1738
1532-1738
DOI:10.1177/10820132241264419