An updated review on 1,2,3-/1,2,4-triazoles: synthesis and diverse range of biological potential

• Published in: Molecular diversity 2024-07
• Main Authors: Raman, Anirudh Pratap Singh, Aslam, Mohd, Awasthi, Amardeep, Ansari, Anas, Jain, Pallavi, Lal, Kashmiri, Bahadur, Indra, Singh, Prashant, Kumari, Kamlesh
• Format: Article
• Language: English
• ISSN: 1381-1991; 1573-501X; 1573-501X
• DOI: 10.1007/s11030-024-10858-0

The synthesis of triazoles has attracted a lot of interest in the field of organic chemistry because of its versatile chemical characteristics and possible biological uses. This review offers an extensive overview of the different pathways used in the production of triazoles. A detailed analysis of recent research indicates that triazole compounds have a potential range of pharmacological activities, including the ability to inhibit enzymes, and have antibacterial, anticancer, and antifungal activities. The integration of computational and experimental methods provides a thorough understanding of the structure-activity connection, promoting sensible drug design and optimization. By including triazoles as essential components in drug discovery, researchers can further explore and innovate in the synthesis, biological assessment, and computational studies of triazoles as drugs, exploring the potential therapeutic significance of triazoles.