Prevalence and Outcome of Secondary Hypogonadism in Male Patients with Cushing's Syndrome and Mild Autonomous Cortisol Secretion

Secondary hypogonadism (SH) is common in men with Cushing's syndrome (CS), but its impact on comorbidities is largely unknown and longitudinal data are scarce. If SH also affects men with mild autonomous cortisol secretion (MACS) is unknown. We included 30 treatment-naïve adult men with CS and...

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Published in:European journal of endocrinology 2024-08, Vol.191 (2), p.232-240
Main Authors: Nowak, Elisabeth, Vogel, Frederick, Braun, Leah, Zopp, Stephanie, Rubinstein, German, Schilbach, Katharina, Bidlingmaier, Martin, Zimmermann, Petra, Thorsteinsdottir, Jun, Schweizer, Júnia, Ritzel, Katrin, Beuschlein, Felix, Reincke, Martin
Format: Article
Language:English
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Summary:Secondary hypogonadism (SH) is common in men with Cushing's syndrome (CS), but its impact on comorbidities is largely unknown and longitudinal data are scarce. If SH also affects men with mild autonomous cortisol secretion (MACS) is unknown. We included 30 treatment-naïve adult men with CS and 17 men with MACS diagnosed since 2012. Hypogonadism was diagnosed based on total testosterone (TT) concentrations
ISSN:0804-4643
1479-683X
1479-683X
DOI:10.1093/ejendo/lvae097