Disability and Quality of Life Measures in older frail and prefrail people with type 2 diabetes. The MIDFRAIL-Study

To explore the individual response to a multimodal intervention on quality of life (QOL) and disability. 843 (77.83 years, 50.65 % men) prefrail and frail individuals ≥ 70 years with type 2 diabetes mellitus. Participants were randomized to the usual care group (UCG) or the multicomponent interventi...

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Bibliographic Details
Published in:Diabetes research and clinical practice 2024-08, Vol.214, p.111797, Article 111797
Main Authors: Sinclair, Alan J., Laosa, Olga, Antonio Carnicero, Jose, Rodriguez-Mañas, Leocadio, Álvarez-Bustos, Alejandro
Format: Article
Language:English
Subjects:
Diabetes
Disability
Frailty
Quality of life
Response-to-treatment
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Summary:To explore the individual response to a multimodal intervention on quality of life (QOL) and disability. 843 (77.83 years, 50.65 % men) prefrail and frail individuals ≥ 70 years with type 2 diabetes mellitus. Participants were randomized to the usual care group (UCG) or the multicomponent intervention (IG). Intervention consisted in 16-week progressive resistance training program, 7 educational sessions and the achievement of HbA1c (7–8 %, 53–64 mmol/mol)) and BP ( 84.38 % was needed for achieving the benefits in Barthel Index. IG has proven to be effective in increasing QOL and avoiding the worsening of QOL and basic ADL.
ISSN:0168-8227
1872-8227
1872-8227
DOI:10.1016/j.diabres.2024.111797