Effect of an evidence-based early rehabilitation program on adult patients with venovenous extracorporeal membrane oxygenation: A cohort study

• Published in: Intensive & critical care nursing 2024-10, Vol.84, p.103744, Article 103744
• Main Authors: Liu, Ying, Xin, Chen, Wei, Lili, Guo, Xiaojing, Zhang, Yuchen, Zhang, Meng, Xing, Jinyan, Gai, Yubiao
• Format: Article
• Language: English
• Subjects: Adult; Anesthesia; Atrophy; Beds; Clinical medicine; Cohort analysis; Cohort Studies; Control groups; Critical care; Critical incidents; Efficacy; Extracorporeal membrane oxygenation; Extracorporeal Membrane Oxygenation - methods; Extracorporeal Membrane Oxygenation - statistics & numerical data; Feasibility; Female; Humans; ICU-aqauired weakness; Intensive care; Intensive Care Units - organization & administration; Intensive Care Units - statistics & numerical data; Intervention; Male; Measurement; Mechanical ventilation; Middle Aged; Nurses; Patients; Physicians; Quality of life; Rehabilitation; Transplants & implants; Ultrasonic imaging; Ultrasonography - methods; Ultrasound; Veins & arteries; Venovenous Extracorporeal Membrane Oxygenation; Ventilation; Ventilators
• ISSN: 0964-3397; 1532-4036; 1532-4036
• DOI: 10.1016/j.iccn.2024.103744

To assess the efficacy of early rehabilitation program for VV-ECMO patients and observe the influence on the respiratory and skeletal muscles. A cohort study. The study was conducted with VVECMO patients in a comprehensive ICU with 32 beds. Ultrasound measurements were performed on each patients on day 1, 4, 7, 10, and 14, including diaphragmatic excursion (DE), diaphragmatic thickening fraction (DTF), intercostal muscle thickening fraction (ICMTF), thickness of the rectus femoris (RF), thickness of vastus intermedius (VI), and rectus femoris cross-sectional area (RF-CSA). Data on basic characteristics, results of ultrasound measurements, patients outcomes and adverse events were collected. 22 patients received usual rehabilitation measures were set as the control group and 23 patients underwent early rehabilitation program were set as the study group. There were no differences in diaphragmatic excursion, diaphragmatic thickening fraction, intercostal muscle thickening fraction, thickness of rectus femoris, thickness of vastus intermedius, rectus femoris cross-sectional area between two groups on day 1 after VV-ECMO treatment (P > 0.05). The variation of diaphragmatic thickening fraction and intercostal muscle thickening fraction decreased on the day 7 and 14 after treatment (P